2,4,6-Trinitrotoluene mutagenic

Spanggord RJ, Mortelmans KE, Griffin AF, et al. 1982b. Mutagenicity in Salmonella typhimurium and structure-activity relationships of wastewater components emanating from the manufacture of trinitrotoluene. Environ Mutagen 4 163-179. 

Kaplan, D. L. Kaplan, A. M. (1982a). Mutagenicity of 2,4,6-trinitrotoluene surfactant complexes. Bulletin of Environmental Contamination and Toxicology, 28, 33-8. 

Padda RS et al., Mutagenicity of trinitrotoluene and metabolites formed during anaerobic degradation by Clostridium acetobutylicum ATCC 824, Environ. Toxicol. Chem., 19, 2871, 2000. 

Tan EL et al., Mutagenicity of trinitrotoluene and its metabolites formed during composting, J. Toxicol. Environ. Elealth, 36, 165, 1992. 

Karamova NS, Il inskaya ON, and Ivanchenko OB, Mutagenic activity of 2,4,6-trinitrotoluene The role of metabolizing enzymes, Russ. J. Genet., 30, 785, 1994. 

Einisto P, Role of bacterial nitroreductase and O-acetyltransferase in mine mutagenicity assay of rats exposed to 2,4,6-trinitrotoluene (TNT), Mut. Res., 262,167,1991. 

Berthe-Corti L et al., Cytotoxicity and mutagenicity of a 2,4,6-trinitrotoluene (TNT) and hexogen contaminated soil in S. typhimurium and mammalian cells, Chemosphere, 37, 209, 1998. 

Frische T, Screening for soil toxicity and mutagenicity using luminescent bacteria—A case study of the explosive 2,4,6-trinitrotoluene (TNT), Ecotoxicol. Environ. Saf., 51, 133, 2002. 

Washburn KS et al., A study of 2,4,6-trinitrotoluene inhibition of benzo[a]pyrene uptake and activation in a microbial mutagenicity assay, Chemosphere, 44,1703, 2001. 

Kaplan DL and Kaplan AM, 2,4,6-trinitrotoluene-surfactant complexes Decomposition, mutagenicity and soil leaching studies, Environ. Sci. Technol., 19, 566, 1982. 

There is a demand for rapid detection of explosives, especially for environmental restoration and humanitarian demining. Among these compoimds, trinitrotoluene (TNT) has attracted a great deal of attention as a main constituent of most of antipersonnel landmines and due to its toxic, mutagenic, and carcinogenic effects. 

Kaplan DL, Kaplan AM. (1982). 2,4,6-Trinitrotoluene-surfactant complexes Deconposition, mutagenicity, and soil leaching studies. Environmental Science and Technology 16 566-571. 

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