Trimethylene carbonate bulk

Glass transition temperature Thermogravimetric analysis Tetrahydrofuran Melting temperature Trimethylene carbonate bulk Theoretical oxygen demand Terephthalic acid... 

Polyglyconate (5) is made by the bulk copolymerisation of a mixture of 67% glycoHde and 33% trimethylene carbonate. The suture is distributed under the trade names Maxon and Maxon CV. It is claimed to retain approximately 50% of its strength four weeks after implantation, 25% at six weeks, and to be essentially completely absorbed ia six months. 

Glycomer-631 (6) is a terpolymer produced by the bulk polymerisation of a mixture of 60% glycoHde, 14% 2,5- -dioxanone, and 26% trimethylene carbonate. The suture is distributed under the trade name Biosyn. It is claimed to retain approximately 40% of its strength three weeks after implantation and to be absorbed completely in 90 to 110 days. 

Deng, F., and Gross, R.A. (1999) Ring-opening bulk polymerization of epsilon-caprolactone and trimethylene carbonate catalyzed by lipase Novozym 435. Int.J. Biol. Macromol., 25, 153-159. 

There has been a significant effort to copolymerize TMC with lactones and other carbonate monomers. Matsumura et al. performed copolymerizations of lactide with TMC using porcine pancreatic lipase at 100°C for 168h [113]. They obtained random copolymers with Mw values up to 21000. However, since trimethylene carbonate is known to thermally polymerize at 100 °C (see above), the extent of polymerization that occurs due to activation of monomers at the lipase catalytic triad versus by thermal or other chemical processes is not known [95], Lipase AK-catalyzed copolymerizations of l,3-dioxan-2-one (TMC) with 5-methyl-5-benzyloxycarbonyl-l,3-dioxan-2-one (MBC) were carried out in bulk at 80 °C for 72 h (Scheme 4.27). Although TMC reacted more rapidly than MBC, the product isolated at 72 h appeared to have a random repeat unit distribution [102], Similarly, using Novozym 435 in toluene at 70°C, TMC/PDL copolymerizations were performed and gave random copolymers. 

Furthermore, the ring-opening co-polymerization of BTMC with 5,5-dimethyl-trimethylene carbonate (DTC) by immobilized porcine pancreatic lipase (0.1 wt%) catalyzed in bulk copolymerization at 150°C for 24h [117]. Under these conditions, the highest molecular weight of poly(BTMC-co-DTC) of M =26 400 was obtained, with 83% monomer conversion. 

IPPL with different size were employed for ring-opening copolymerization of 5-benzyloxy-trimethylene carbonate (BTMC) with 5,5-dimethyl-trimethylene carbonate (DTC) in bulk (33). 

Yu F, Zhuo R (2004) Synthesis and characterization of OH-Terminated poly(trimethylene carbonate)s by alcohol-initiated ring-opening polymerization in melt bulk without using any catalyst. Polym J 36 28-33... 

The polymerization of trimethylene carbonate (l,3-dioxan-2-one) with complex-ation catalysts has been discussed [288]. The bulk polymerization of trimethylene carbonate was conducted at 90, 120, and 150 °C in the presence of initiators. In... 

The six-membered lactide, a cyclic dimer of lactic acid, was polymerized by lipase as a catalyst in bulk to yield the corresponding polylactide with an of up to 126000 with a relatively low yield. The D,L-lactide gave a higher molecular weight compared to the D,D- and L,L-lactides [45,46]. The L,L-, D,D-, and D,L-lactides were copolymerized with trimethylene carbonate by porcine pancreatic lipase (PPL) to produce random copolymers having molecular weights of up to 21000 [47]. 

L-valine, L-proline, L-leucine, and L-phenylalanine as initiators of the ROP of DTC and TMC. PTMC and poly(dimethyl trimethylene carbonate) (PDTC) with different Mn were obtained at 80 and 120 °C, respectively, in bulk by changing the molar ratio of [monomer]/[amino acid]. Among these polymers, the maximum values of A n of the PCs reached 17 800-18 900 and the dispersity index was 1.67 for [monomer]/[r-phenylalanine] molar ratio of 200. NMR spectroscopic analysis demonstrated that amino acid was incorporated into the polymer chain. 

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