Triglyceride metabolism

Binnert, C., Laville, M., Pachiaudi, C., Rigalleau, V. and Beylot, M. (1995) Use of gas chromatography isotope ratio mass spectrometry to study triglyceride metabolism in humans. Lipids 30, 869 873. 

Auwerx, J., Schoonjans, K., Fruchart, J. C., and Staels, B. (1996). Transcriptional control of triglyceride metabolism Fibrates and fatty acids change the expression of the LPL and apo C-111 genes by activating the nuclear receptor PPAR. Atherosclerosis 124(Suppl.), S29-S37. 

Ginsberg HN. Effects of statins on triglyceride metabolism. AmJ Cardiol. 1998 81(4A) 32B-35B. 

Effect of DHA on hepatic triglyceride metabolism in diet-induced... 

EFFECT OF DHA ON HEPATIC TRIGLYCERIDE METABOLISM IN DIET-INDUCED LIPODYSTROPHY MODEL MICE... 

G.A. Langner, E.h. Birkenmeier, O. Ben-Zeev, M.C. Schotz, H.O. Sweet, M.T. Davisson, and J.L Gordon, The fatty liver dystrophy (fid) mutation. A new mutant mouse with a developmental abnormality in triglyceride metabolism and associated tissue-specific defects in lipoprotein lipase and hepatic lipase activities, J. Biol. Chem., 1989, 264, 7994-8003. 

Zhang, Y., Castellani, L. W., Sinai, C. J., Gonzalez, F. J., and Edwards, P. A. (2004) Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR. Genes Dev. 18, 157-169. 

Although humans store most of their energy as fatty acids within triglycerides, metabolic machinery to convert these into carbohydrates is not present. Fatty acids are catabolized to acetyl-CoA via P-oxidation (Sec. 10.5), and the overall reaction of the pyravate dehydrogenase complex is irreversible. 

Patsch JR, Miesenbock G, Hopferwieser T, et al. Relation of triglyceride metabolism and coronary artery disease studies in the postprandial state. Arterioscler Thromb 1992 12 1336-1345. 

Patsch, J. R., Miesenbock, G., Hopferwieser, T., Muhlberger, V., Knapp, E., Dunn, J. K., Gotto, A. M., Jr., and Patsch, W. (1992). Relation of triglyceride metabolism and coronary artery disease. Studies in the postprandial state. Arterioscler. Thromb. 12,1336-1345. 

Jenkins, D.L. Griffith, O.W. (1985) J. Biol. Chem. 260, 14748-14755. DL-Aminocamitine and acetyl-DL-aminocamitine. Potent inhibitors of carnitine acyltransferases and hepatic triglyceride metabolism. 

Manco M, Mingrone G, Greco AV, et al. Insulin resistance directly correlates with increased saturated fatty acids in skeletal muscle triglycerides. Metabolism, 2000, 49, 220-224. 

The potential use of C-labelled compounds in clinical research has not yet been fully appreciated. There is an increasing demand for C-labelled amino acids to complement N studies of human nitrogen metabolism in addition to C fatty acids, which would permit the study of fatty acid and triglyceride metabolism to be extended to patients in whom the use of C analogues are ethically unacceptable. One of the few reports involving the use of C-labelled fatty acids employed palmitic and oleic acids to study fat absorption in a patient with chyluria [308]. These investigators fed (carhox y/- C)-labelled... 

Kashyap ML, Srivastava LS, Hynd BA, Perisutti G, Brady DW, Gartside P, Glueck CJ (1978) The role of high density lipoprotein apolipoprotein C-II in triglyceride metabolism. Lipids 13 933-942... 

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