Trigger sequence

Frank, S., Lustig, A., Schulthess, T., Engel, J., and Kammerer, R. A. (2000). A distinct seven-residue trigger sequence is indispensable for proper coiled-coil formation of the human macrophage scavenger receptor oligomerization domain./. Biol. Chem. 275, 11672-11677. 

Lee, D. L., Lavigne, P., and Hodges, R. S. (2001). Are trigger sequences essential in the folding of two-stranded alpha-helical coiled-coils J. Mol. Biol. 306, 539-553. 

Sequential recording Controlled by an internal clock oscillator, the sequencer counts through a range of subsequent address words. The result is a sequence of waveform measurements. The individual measurements can be multidimensional themselves, due to the capabilities of the channel control. The sequence can be recorded at almost any rate. It can be triggered by an experi-ment trigger", and a specified number of triggered sequences can be accumulated. 

If the stimulation of the system under investigation is repeatable a large number of triggered sequences can be accumulated. With accumulation, a sufficient number of photons per step is obtained even for sequencing rates faster than the count rate. The different time scales are illustrated in Fig. 3.8. Again, multiplexing was omitted for simplicity. 

The analyzer trigger sequence is shown in Fig. 30.10. The base time is taken from a 100-kc oscillator. 

The reaction mechanisms of plasma polymerization processes are not understood in detail. Poll et al [34] (figure C2.13.6) proposed a possible generic reaction sequence. Plasma-initiated polymerization can lead to the polymerization of a suitable monomer directly at the surface. The reaction is probably triggered by collisions of energetic ions or electrons, energetic photons or interactions of metastables or free radicals produced in the plasma with the surface. Activation processes in the plasma and the film fonnation at the surface may also result in the fonnation of non-reactive products. 

Detecting transducers at the measuring points are electrical, pneumatic, or hydraulic. The resultant circuits and sequences can be seen from the typical functional diagram in Figure 4-34. An emergency shutdown immediately triggers the following operations ... 

In the previous chapter, a comprehensive description was provided, from four complementary perspectives, of the process of how human errors arise during the tasks typically carried out in the chemical process industry (CPI). In other words, the primary concern was with the process of error causation. In this chapter the emphasis will be on the why of error causation. In terms of the system-induced error model presented in Chapter 1, errors can be seen as arising from the conjunction of an error inducing environment, the intrinsic error tendencies of the human and some initiating event which triggers the error sequence from this imstable situation (see Figure 1.5, Chapter 1). This error sequence may then go on to lead to an accident if no barrier or recovery process intervenes. Chapter 2 describes in detail the characteristics of the basic human error tendencies. Chapter 3 describes factors which combine with these tendencies to create the error-likely situation. These factors are called performance-influencing factors or PIFs. 

Kumar, S., et al. (1990). Amino acid sequence of the calcium-triggered luciferin binding protein of Renilla reniformis. FEBS Lett. 268 287-290. 

Proteins that bind DNA at specific DNA sequences often distal from transcriptional start sites of genes. Their binding and activity is usually cell type or stimulus triggered, which subsequently decondensate the chromatin and finally lead to the recruitment of general transcription factors and the RNA polymerase. 

A sequence stretch 300 base pairs upstream of the transcriptional start site suffices for most of the transcriptional regulation of the IL-6 gene (Fig. 1). Within this sequence stretch several transcription factors find their specific recognition sites. In 5 to 3 direction, AP-1, CREB, C/EBP 3/NF-IL6, SP-1 and NF-kB can bind to the promoter followed by TATA and its TATA binding protein TBP. Most enhancer factors become active in response to one or several different stimuli and the active factors can trigger transcription individually or in concert. For example, AP-1 is active upon cellular stress, or upon stimuli that tell cells to proliferate CREB becomes also active if cells experience growth signals, but also upon elevation of intracellular levels of cyclic adenosine monophosphate (cAMP), which occurs upon stimulation if so called hormone-activated G protein-coupled receptors. 

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