TRH thyrotropin-releasing

EGF Epidermal growth factor TRH Thyrotropin-releasing hormone... 

Various amino acids have been replaced by 4-F-Phe or hexafluorovaline in peptidic hormones oxytocin (4-F-Phe —> lyr), bradykinin (4-F-Phe —> Phe), and angiotensin II. The consequences are diverse, but the stability toward hydrolytic enzymes is generally enhanced. Thus, incorporation of Fs-valine in an octapeptide antagonist of angiotensin II (Sar-AII) notably enhances its in vivo antagonist activity. Analogues of TRH (thyrotropin-releasing hormone), in which histidine is replaced by a fluor-ohistidine (4-F-His and 2-F-His —> His), have better in vivo activities, while the affinities are lower. 

PIP2 = phosphatidyUnositol-4,5-biphosphate TRH = thyrotropin-releasing hormone. 

Note. CBZ = carbamazepine NMDA = N-methyl-D-aspartate NPY = neuropeptide Y TRH = thyrotropin-releasing hormone (- = equivocal. 

TR 82, TR/31, TRal thyroid hormone receptors TRH thyrotropin-releasing hormone TSAb thyroid-stimulating antibody TSH thyroid-stimulating hormone... 

CRH, corticotropin-releasing hormone GABA, y-aminobutyric acid CnRH, gonadotropin-releasing hormone IGF-I, insulin-like growth factor MAO, monoamine oxidase TRH, thyrotropin-releasing hormone VIP, vasoactive intestinal peptide. 

TRH Thyrotropin-releasing hormone a tripeptide hormone that is released by the hypothalamus and that acts on the anterior pituitary to stimulate the release of thyroid-stimulating hormone. 

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