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Transgenic plants, seed storage proteins

Vandekerckhove J, Van Damme J, Van Lijse-betten M, et al. Enkephalins produced in transgenic plants using modified 2S seed storage proteins. Bio/Technology 1989 7 929-932. [Pg.886]

As it is imperative that the plant-derived hiopharmaceutical product must be obtained repeatedly and on a consistent basis, a master cell culture bank, seed bank for transgenic plants, or virus seed stock for transient expression systems must be constantly maintained. Storage conditions must therefore he optimized to prevent contamination and ensure viability. Both transgene stability (e.g., reversion to wild type or sequence drift of plant virus expression vectors) and protein expression levels must be monitored in a representative plant of a given bank or stock to minimize any possible variation in expression levels that may affect safety and consistency of the hnal product. A program that monitors lot-to-lot consistency of the hiochemical and biological properties by comparing the product with appropriate in-house reference standards could he implemented as a fundamental component of product development. [Pg.184]


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Plants storage proteins

Seed storage proteins

Seeds proteins

Storage plants

Transgenic seed

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