Trans-aconitic acid

Koh, H. S., M. Kim, T. Obata, H. Fukami, and S. Ishii. Antifeedant in barnyard grass against the brown planthopper-trans-aconitic acid. Rice Brown Planthopper (Pap Semin) 1976 Food Fert Technol Center Asian Pac Reg, Taipei, Taiwan. 

Krogh, A. 1971. The content of trans-aconitic acid in Asarum europaeum L. determined by means of a chromatogram spectrophotometer. Acta Chem. Scand. 25 1495-1496. 

In contrast, GLH eggs tolerated trans-aconitic acid levels which were lethal to BPH eggs. In nature, GLH thrives on barnyard grass. 

Figure 7. Effect of trans-aconitic acid, a barnyard grass chemical, on hatching of eggs of three biotypes of N. lugens.

MaUc, succinic, citric, trans-aconitic acid C1-C4 mono-carboxylic, lactic, pyruvic, citric, fumaric, malic, succinic,... 

Long chain hydrocarbons and fatty acids are best known as constitutents of waxes and lipophilic compounds. Some representatives of this natural product group show high antiprotozoal activity but mostly combined with a high levels of toxicity to mammalian cells. One example is traws-aconitic acid (2) that was used in combination with sodium stibogluconate, allopurinol, or pentamidine for experimental visceral leishmaniasis to determine synergistic effects [34]. When these three drugs (50, 15, 8 mM/kg/day, respectively) were used with trans-aconitic acid (5 mM/kg/day) the parasite load in BALB/c mice was inhibited by 100, 88, and 100%, respectively. At tested concentration trans-aconitic acid itself showed an inhibition of 59.2 %. 

CsH OJ- COOH H2c4 COOH °Co-y-irr. of trans-aconitic acid/ Neat EPR/ 300 H(l, 1, 3) 1.4 66Chal... 

Table 10.12 trans-Aconitic acid, NaOH buffer (23 C) ... 

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