Topoisomerase targeting drugs

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Zhang, H., Pan, Y Affinity ultrafiltration of DNA topoisomerases-targeted compounds determined with HPLC/ESI-MS for drug candidate screening. J. Zhqiang Univ. Sci. 2004, 5, 900-905. 

Chen AY, Choy H, Rothenberg ML. DNA topoisomerase I-targeting drugs as radiation sensitizers. Oncology (Huntingt) 1999 13 39—46. 

Topoisomerase Interactive Drugs. Topoisomerases I and II have emerged as interesting targets for the design of new anticancer agents (Table 4),... 

Determinants of Sensitivity to Topoisomerase-Targeting Antitumor Drugs Peter D Arpa... 

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A. Maxwell, D. M. Lawson (2003). The ATP-binding site of type II topoisomerases as a target for antibacterial drugs. Curr. Top. Med. Chem. 3 283-303. 

Zhou, Z., Jia, S.-F, Hung, M.-C., and Kleinerman, E. S. 2001. E1A sensitizes HER2/new-overex-pressing Ewing s sarcoma cells to topoisomerase II-targeting anticancer drugs. Cancer Res. 67 3394-3398. 

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