Topical Drugs Used in the Treatment of Skin Disorders

Topical Drugs Used in the Treatment of Skin Disorders 

Localized skin infections may require the use of a topical anti-infective The topical anti-infectives include antibiotic, antifungal, and antiviral drag s. 

Topical antibiotics exert a direct local effect on specific microorganisms and may be bactericidal or bacteriostatic. Bacitracin (Baciguent) inhibits the cell wall synthesis. Bacitracin, gentamicin (G-myticin), erythromycin (Emgel), and neomycin are examples of topical antibiotics. These drugp are used to prevent superficial infections in minor cuts, wounds, skin abrasions, and minor burns. Erythromycin is also indicated for treatment of acne vulgaris. 

Antifungal drugp exert a local effect by inhibiting growth of the fungi. Examples of antifungal drugs and their uses are  

U N IT XI Drugs That Affect Other Body Systems 

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Unit XI consists of three chapters that discusses types of drugs not previously discussed or that are not members of a particular class or group. Chapters in this unit include topical drugs used in the treatment of skin disorders, otic and ophthalmic preparations, and fluids and electrolytes. 

CHAPTER 56 Topics Drugs Used in the Treatment of Skin Disord s... 

Topical antipsoriatics are drugs used in the treatment of psoriasis (a chronic skin disease manifested by bright red patches covered with silvery scales or plaques). These drug help remove tiie plaques associated with this disorder. Examples of antipsoriatics include antiiralin (Anthra-Derm) and calcipotriene (Dovonex). 

The widespread applicability of di-O-methylisosorbide as a medium for chemical reactions or as a solvent for pharmaceutical formulations is well documented. In some cases, an additive synergism of the solvent and the solute was observed. Some typical examples mentioned include that it acts as a solvent for muscle-relaxant drugs, which are otherwise difficultly soluble,226 and is used for topical and other types of pharmaceutical formulations,227,228 transdermal controlled-release films229 and tapes,230 anthelmintic solutions,231 antimycotic emulsions,232 and for the treatment of skin disorders, such as eczema.233... 

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