TOKYO,UNIVERSITY TECHNOLOGY

Department of chemical engineering, Graduate School of Bio-Applications and Systems Engineering, Tokyo University of Agriculture and Technology, 24-16-2 Naka-machi, Koganei-shi, Tokyo 184-8588, Japan... 

Ken Tanaka, Tokyo University of Agriculture and Technology, Tokyo, Japan... 

State University Ghent (Belgium), 301 Technical University of Lodz (Poland), 467 Tokyo University of Agriculture and Technology, 207 TosoHaas, 152... 

Tokyo University of Agriculture and Technology, 251 Thfts Univeisity, 364 University di Ferrara, 72 University di Torino, 72 Universitat Bremen, 43,210... 

The authors would like to thank our project members ftom National Institute of Advanced Industrial Science and Technology (AIST), Toppan Printing Co. Ltd, Sharp Corporation, Astellas Pharma Inc., Tokyo University of Technology and Kumamoto University. This work was financially supported by the New Energy and Industrial Technology Development Organization (NEDO), Japan. 

The Wittig reaction efficiently olefinates aldehydes and ketones, but not esters or amides. Several early-transition-metal approaches have been taken to this problem. Recently, Takeshi Takeda of the Tokyo University of Agriculture and Technology reported (Tetrahedron Lett. 44 5571,2003) that the titanocene reagent can effect the condensation of an amide 10 with a thioacetal 11 to give the enamine 12. On hydrolysis, 12 is converted into the ketone 13. When the reaction is intramolecular, reduction proceeds all the way, to give the pyrrolidine IS. 

Steven Brown, M.S. (1974), Research Associate, University of Kentucky, Lexington, KY Richard Harrington, M.S. (1974), 112 306 Baxter Court, Chaska, MN Yoshiyuki Sakano, Post-D. (1974-1975), Faculty of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Tokyo, Japan Yuk-Charn Chan, Ph.D. (1975), Research Biochemist, American Critical Care, McGrew Park, IL... 

Food Science and Technology Department, Tokyo University of Fisheries Konan 4, Minato, Tokyo 108 Japan... 

Koichi Yoneyama, Utsunomiya University, Utsunomiya, Japan Masahiro Natsume, Tokyo University of Agriculture and Technology, Tokyo, Japan J 2010 Elsevier Ltd. All rights reserved. 

Yukinobu Fukaya, Department of Biotechnology, Tokyo University of Agriculture Technology yuki-f cc.mat.ac.jp... 

Takuya Nakashima, Research and Education Center for Materials Science, Nara Institute of Science and Technology ntaka ms.naistjp Asako Narita, Department of Biotechnology, Tokyo University of Agriculture Technology nariasa cc.tuat.ac.jp... 

I would like to extend my appreciation to all members of our laboratory in the Department of Biotechnology, Tokyo University of Agriculture and Technology. Especially Dr. M. Yoshizawa receives my most sincere thanks. This book would not have been hnished without his sacrihces. Last I would like to thank Dr. Arza Seidel of John Wiley and Sons, Inc. for her kind support and encouragement. 

Department of Applied Chemistry, Tokyo University of Science, Tokyo,1-3 Kagurazaka, Shinjuku-ku, Tokyo 162-8601, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency (CREST, JST), 4-1-8 Honcho, Kawaguchi-shi, Saitama 332-001, Japan... 

Montagnini, F. 1994. Rehabilitating forest ecosystems in the humid tropics Recent experiences from Latin America. In Proceedings from lUFRO International Symposium on Growth and Yield of Tropical Forests. Sept. 26-Oct. 1, 1994 (Tokyo University of Agriculture and Technology. Fuchu, Tokyo, Japan), pp. 224-234. 

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