Todd, Sir Alexander

TODD, SIR ALEXANDER R. (1907-1997). A British chemist who won the Nobel prize for chemistry in 19.57. His diverse research and accomplishments involved phosphorylation and mechanisms of biological reactions concerning phosphates. Many of his studies concerned the structure of nucleic acids, nucleotides, nucleotidic coenzynies, as well as vitamins Bj, B12, and E. Work in biological organic chemistry indicated diat hemp plant could be used for production of narcotics. T odd had degrees awarded from Oxford, Frankfurt, and Glasgow, among others. 

Todd, Sir Alexander. Perspectives in Organic Chemistry. Interscience, Inc., New York. 1956. 

Todd, Sir Alexander R. (1907-1997). A British chemist who won the Nobel Prize for chemistry in 1957. His diverse research and accomplishments involved phosphorylation and mechanisms of... 

Todd, Sir Alexander Robertus, (Baron Todd of Trumpinston)... 

Sir Alexander Todd, who won the Nobel Prize for Chemistry in 1957, was a former pupil of Allan Glen s school in Glasgow, where I also got my secondary education. He not only established die chemical structure of nucleic acids, but we owe to him our knowledge of the structures of FAD, ADP and ATP. 

Linus Pauling, "The Nature of the Theory of Resonance," 18, in [Sir] Alexander Todd, ed., Perspectives in Organic Chemistry (New York Interscience Publishers, 1956) 67, regarding Ingold and Ingold (1926), 1312. Todd s volume is dedicated to Robert Robinson on the occasion of his seventieth birthday, September 13, 1956. 

Todd, [Lord] Alexander, and [Sir] John Cornworth. "Robert Robinson." Biographical Memoirs of Fellows of the Royal Society 22 (1976) 465478. 

Studies that determined the structures of the nucleic acids and paved the way for the discovery of the DNA double helix were carried out by Phoebus Levene and elaborated by Sir Alexander Todd. 

Around 1940, cannabinol was isolated independently by Sir Alexander R. Todd (1907-1997) at the University of Manchester and Roger Adams at the University of Illinois. However, it was determined that this compound was not responsible for the psychotropic effects of cannabis, but actually an artefact, which originated by oxidation of THC dru-ing the isolation process. [125] An additional difficulty in determining the structure of THC was, that the double bond isomerises readily in presence of acid into the thermodynamically favoru-ed 8-position. The problem of isolation was simply technical in nature in contrast to the alkaloids, which are readily purifyable by salt formation as crystalline compounds, this is not possible with /4 -tetrahydrocannabmoL... 

The nature of the theory of resonance, in Perspectives in Organic Chemistry, Sir Alexander Todd, ed. Interscience, New York, (1956), 1—8. 

The synthesis of adenosine can be conveniently divided into two parts. The first part is the synthesis of the purine system, while the second part is the attachment of the ribose to the appropriate position of the former. An interesting description of the issue of the phosphorylation (needed for the synthesis of adenosine mono-, di-, and triphosphates) is provided by Sir Alexander Todd in his lecture (December 11,1957) on the occasion of his acceptance of the Nobel Prize and, in principle, might be considered a third part of the overall synthesis problem. 

Pauling, 1956] L. Pauling. The Nature of the Theory of Resonance in Sir Alexander Todd (ed.) Perspectives in Organic Chemistry London Interscience, 1-8, 1956. 

Personal letter from S. S. Schweber, 20 April 1992. Also, [Lord] Alexander Todd, "Summing Up," in Further Perspectives in Organic Chemistry. Ciba Foundation Symposium 53 (new series). To Commemorate Sir Robert Robinson and His Research (Amsterdam Elsevier, 1978) 203204 and Carl Djerassi, lecture at University of Oklahoma, Norman, 19 November 1992. 

---