Tissue engineering scaffolds biomimetic composition

R. Zhang, PX. Ma, Biomimetic polymer/apatite composite scaffolds for mineraUzed tissue engineering, Macromol. Biosci. 4 (2)... 

Thein-Han, W. W. and Misra, R. D. K. 2009. Biomimetic chitosan-nanohydroxyapatite composite scaffolds for bone tissue engineering. Acta Biomat. DOI 10.1016/j.actbio.2008.11.025. 

The recent trend of tissue engineering is the design of biomimetic scaffolds with similar mechanical, stmcmral and chemical properties compared to the natural extracellular matrix (ECM) of the tissue to be regenerated. In the case of PURs, biomimetic properties can be obtained by tuning the PUR block structure and composition, as underlined in the following paragraphs. 

Mouritz, A.P., Bannister, M.K., Falzon, P.J., Leong, K.H., 1999. Review of applications for advanced three-dimensional fibre textile composites. Compos. A Appl. Sci. Manuf. 30,1445-1461. Moutos, F.T., Freed, L.E., Guilak, F., 2007. A biomimetic three-dimensional woven composite scaffold for functional tissue engineering of cartilage. Nat. Mater. 6, 162-167. 

Moutos, F. T., Freed, L. E., and Guilak, F. 2007. A biomimetic three-dimensional woven composite scaffold for functional tissue engineering of cartilage. Nat Mater 6 162-7. 

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