Tissue engineering fabrication techniques

Phase separation is one of the most popular techniques for fabricating porous scaffolds for tissue engineering applications. In this process, phase separation is... 

We have also provided evidence that the behavior of microorganisms in confined micro-environment is substantially different and that their desired metabolic activities can be maximized through the modification of the surface characteristics as well as the size of the pores. These characteristics can therefore be utilized in BI as well as in the enhancement of cell penetration and cell proliferation in tissue engineering and when such polymers are grafted. Micro-fabrication technique has also been used in the development of highly porous catalysts with arterial channels feeding nano-pores which provide an extended surface area. Such materials can be used as micro-reactors as well as catalysts. 

Another useful thermal characterization technique is thermal compression in which a polymer fabric or biotextile is subjected to different loads at different temperatures. The thickness, pore size, and distribution can be monitored at each condition to prepare ideal scaffolds for tissue engineering. PolyCethylene terephthalate) (PET) nonwoven fiber scaffolds have been prepared for tissue engineering by thermal compression and simultaneous characterization. Applying pressure near the T of the polymer ( 70°C) yielded better control of the pore size distribution and smaller pore sizes, which led to faster and wider proliferation of Irophoblast andNIH 3T3 cells on the scaffold [9]. 

B. Frerich, K. Winter, K. ScheHa-, U.D. Braumann, Comparison of different fabrication techniques for human adipose tissue engineering in severe combined immunodeficient mice, Artif. Organs 36 (2012)... 

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