Tissue engineered vascular graft

Chuang TH et al (2009) Polyphenol-stabilized tubular elastin scaffolds for tissue engineered vascular grafts. Tissue Eng Part A 15(10) 2837-2851... 

Zhang X et al (2009) Dynamic culture conditions to generate silk-based tissue-engineered vascular grafts. Biomaterials 30( 19) 3213—3223... 

Mertens ME, Koch S, Schuster P, Wehner J, Wu Z, Gremse F, et al. USPIO-labeled textile materials for non-invasive MR imaging of tissue-engineered vascular grafts. Biorrmterials... 

L Heureux N, Dusserre N, Marini A, Ganido S, de la Fuente LM, McAllister T. Technology insight the evolution of tissue-engineered vascular grafts— from research to clinical practice. Nat Clin Bract Cardiovasc Med 2007 4 389-95. 

Wolfinbarger Jr L. Bioreactor mediated recellularization of natural and tissue engineered vascular grafts. US Patent 7179 287,02/20/2007. 

Campbell GR and Campbell JH. Development of tissue engineered vascular grafts. Curr. Pharm. Biotechnol. 8 43-50,2007... 

K. Torikai, H. Ichikawa, K. Hirakawa, G. Matsumiya, T. Kuratani, S. Iwai, A. Saito, N. Kawaguchi, N. Matsuura, Y. Sawa, A self-renewing, tissue-engineered vascular graft for arterial reconstruction, J. Thorac. Cardiovasc. Surg. 136 (1) (2008) 37—45 el. 

He W, Nieponice A, Soletti L, Hong Y, Gharaibeh B, Crisan M, et al. Pericyte-based human tissue engineered vascular grafts. Biomaterials 2010 31 8235-44. 

As described above, the creation of a tissue-engineered vascular graft (TEVG) usually involves the harvest of desired cells, cell expansion in culture, cell seeding onto a scaffold, culture of the constmct in an environment that induces tissue formation, and implantation of the constmct back into the patient. Many options must be considered for each step in this process. 

McAllister TN, Maruszewski M, Garrido SA, Wystrychowski W, Dusserre N, Marini A, et al Effectiveness of haemodialysis access with an autologous tissue-engineered vascular graft a multicentre cohort study. Lancet 2009 373 1440-1446. 

There are generally three methods of constructing tissue engineered vascular grafts by applying collagen gel, cell-sheet and biodegradable polymer scaffolds. 

Table VII. Requirements for tissue engineered vascular grafts...

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