Thrombus white clot

White clot syndrome - Rarely, patients may develop new thrombus formation in association with thrombocytopenia resulting from irreversible aggregation of platelets induced by heparin, the so-called white clot syndrome. The process may lead to severe thromboembolic complications. Monitor platelet counts before and during therapy. If significant thrombocytopenia occurs, immediately... 

There are several techniques available for mechanical thrombolysis. The most common is probing the thrombus with a microguidewire. This technique appears to be useful in facilitating chemical thrombolysis. Alternatively, a snare (e.g., Amplatz Goose-Neck Microsnare, Microvena, White Bear Lake, MN) can be used for multiple passes through the occlusion to disrupt the thrombus. " A snare can also be used for clot retrieval, mostly in simations in which the clot has a firm consistency or contains solid material. ... 

Venous thromboembolism (VTE) results from clot formation in the venous circulation and is manifested as deep vein thrombosis (DVT) and pulmonary embolism (PE). A DVT is a thrombus composed of cellular material (red and white blood cells, platelets) bound together with fibrin strands. A PE is a thrombus that arises from the systemic circulation and lodges in the pulmonary artery or one of its branches, causing complete or partial obstruction of pulmonary blood flow. 

ICAM-1, ICAM-2) and vascular cell adhesion molecule (VCAM). Platelets are attracted to damaged endothelium where they adhere to prevent blood loss in a similar fashion to white blood cells, i.e. via adhesion molecule interactions, to form a clot (thrombus). 

Platelet adhesion to vessel walls and the subsequent release of adenosine diphosphate (ADP) initiates the formation of the arterial (white) thrombus. The arterial thrombus grows as platelets aggregate. As the thrombus occludes blood flow, it is surrounded by a "red" clot, composed of fibrin, platelets and erythrocytes. Like atherosclerotic plaques, arterial thrombi occlude blood vessels, causing tissue ischemia. 

The blood clot formed in a test tube is strikingly different from a thrombus deposit formed in vivo in the vascular system. A clot in a test tube consists of a fibrin network in which red cells, white cells, and relatively small numbers of platelets are found. On the other hand, an in vivo thrombus deposit consists of large amorphous masses of platelets, surrounded by white cells with a few red cells. However, it is possible to form deposits closer to thrombi rather than to blood clots in vitro by using circulating plastic loops in which the blood is in motion during coagulation. ... 

Irreversible permanent clot (white thrombus) Red thrombus... 

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