Thioridazine constipation with

The other side effects include epileptic seizures, disturbances in body temperature regulation. ANS side effects include tachycardia, difficulty in micturition, inhibition of ejaculation, postural hypotension, blurring of vision (with thioridazine), constipation, nasal stuffiness etc. 

Ziprasidone is well tolerated. Its common side effects are drowsiness, nausea, and constipation. Though there were initial concerns about untoward cardiological side effects similar to those produced by thioridazine and the tricyclic antidepressants, ziprasidone appears to be safe though it should probably not be used in patients with preexisting heart disease. 

Nausea, which may be patient related, occurs frequently with psychotropic drugs, but the incidence is also high in schizophrenic patients who are receiving placebo. Furthermore, the incidence of vomiting with thioridazine, which has no antiemetic effect, is high. Dry mouth, constipation, paralytic ileus, and decreased gastric secretion, which are all due to its anticholinergic effects, may occur. 

Clinically relevant interactions were not noted when moclobemide was given with one or more neuroleptics (including phenothiazines such as chlorpromazine, levomepromazine, thioridazine). Adverse effects such as hypotension, tachycardia, drowsiness, tremor, and constipation were somewhat more Sequent, probably due to additive effects. A fatal case of overdose with moclobemide and perazine was attributed to syn-ergisSc effects resulSng in funcSonal cardiovascular disorder. ... 

The manufacturer of moclobemide noted that in 1992 there were data available from 110 patients given moclobemide 150 to 400 mg daily with various antipsychotks, namely acepromazine, aceprometazine, alimemazine, bromperidol, chlorpromazine, chlorprothixene, clothiapine, clozapine, cyamemazine, flupen-thixol, fluphenazine, fluspirilene, haloperidol, levomepromazine, penfluridol, pipamperone, prothipendyl, sulpiride, thioridazine, or zuclopenthixoL There was no evidence of any clinically relevant interactions. There was, however, some evidence that hypotension, tachycardia, sieepiness, tremor and constipation were more common, suggesting synergistic adverse effects. ... 

---