Thiols preparation

Examples of thiols prepared using this type of technology are 2-methyl-l-propanethiol, 1-butanethiol, and 2-butanethiol, in equations 3—5, respectively. 

Methanethiol (eq. 6) and cyclohexanethiol (eq. 7) are the only commercially important thiols prepared using alcohol substitution. In most cases, when the alcohol is utilized, less control over the substitution patterns is obtained. Only one isomer is obtainable in the case of methanol and cyclohexanol. 

Figure 5.2 STM images ofthiols SAM on Au/mica illustrating the range of structural qualities, (a) high-quality SAM of dodecane thiol prepared from a solution of dodecane thiocyanate [111] and a low-quality aromatic SAM of methylbiphenyl butane thiol (MBP4) (b) [90].

The catalytic propargylic alkylation was investigated in the presence of thiolate-bridged diruthenium complexes as catalysts generated in situ from reactions of [Cp RuCl(p2-Cl)]2 with optically active thiols prepared from the corresponding optically active alcohols [27]. Typical results for the reaction of 1-phenyl-2-propyn-l-ol with acetone in the presence of a variety of catalysts are shovm in Scheme 7.19. 

TABLE 1. Physical Properties of Step 1 Products Prepared by Condensing Diphenyl Carbonate with Selected Thiols Prepared According to the Current Invention... 

Starch thiols can have the SH group directly on the pyranose ring or in a side chain. There are several methods of synthesizing starch thiols of the first type. One of them is based on the pyrolysis of starch xanthates (32), but the reaction proceeds in two parallel routes one producing thionates (35) and the other producing thiols (37).2675,2677 Reduction of starch xanthates with NaBPU in alkali is another approach to thiols. Thiols prepared in this manner were subjected to graft polymerization with vinyl polymers. Nucleophilic substitution of the chlorine... 

Hieber, W., and Kaiser, K., Preparation and composition of polynuclear halo-genated iron carbonyl sulfides and thiols, preparation of [Fe3(CO)eS2X4]+... 

In 1840 Regnault passed ethyl chloride into potassium hydrogen sulphide in a retort and obtained ethanethioP (equation 29). This classical synthetic method has been used to prepare labelled thiols from Na SH and organic halides. The thiols prepared by this method include... 

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