Thiolate ligand

Sequence analysis and mutagenesis experiments indicated that the thiolate ligand is provided by a-Cys-275 (163—165). These predictions have been... 

They doubtless owe their stability to the bulk of the aryl thiolate ligand they have tbp structures with equatorial nitrile that can be displaced by CO to give rare carbonyls of a metal in the +4 oxidation state. 

The halides in mer-OsCl3(PR3)3 can be replaced by a thiolate ligand to give paramagnetic Os(SC6F5)3(PR3)2 an agostic Os—F—C interaction is believed to complete the coordination sphere of osmium [156]. 

Spectroscopic studies have been instrumental in elucidating the catalytic mechanism of Ni-Fe hydrogenases. A great deal of controversy concerning this mechanism arises from the fact that, as the as the X-ray crystallographic analysis has shown, there are at least three potential redox-active species at the enzyme s active site the thiolate ligands (75) and the Fe (65) and Ni (9) ions. 

Complexes of Sterically Hindered Thiolate Ligands J. R. Dilworth and J. Hu... 

D., Yang, C.-T, Ranford, J.D., Vittal, J.J. and Lee, P.F. (2003) Synthesis, characterization, and biological activities of 2-phenylpyridine gold(lll) complexes with thiolate ligands. Dalton Transactions, (17), 3376. 

Bardaji, M., Laguna, A., Perez, M.R. and Jones, P.G. (2002) Unexpected Ring-Opening Reaction to a New Cyanamide-Thiolate Ligand Stabilized as a Dinuclear Gold Complex. Organometallics, 21(9), 1877-1881. 

I) complexes with biologically active thiolate ligands. Inorganica Chimica Acta, 258(1), 71-75. 

Pan, Q.-J. and Zhang, H.-X. (2003) Aurophilic attraction and excited-state properties of binuclear Au(I) complexes with bridging phosphine and/or thiolate ligands An ah initio study. Journal of Chemical Physics, 119, 4346-4352. 

Gold(I) thiolates in the thiolate gold ratio of 1 1 or 2 1 were the first chrysother-apeutic agents to be used. They are administered intramuscularly and not orally because they cannot be readily absorbed from the gut and by other tissues. Table 6.1 lists some chrysotherapy agents that will be discussed, with their formulae and Figure 6.1 shows chemical structures for some important thiolate ligands. 

The numbers of gold atoms and thiolate ligands for 1-22 are plotted in Figure 6. 

The reaction of thiolate ligands with [Ni(terpy)Cl2] in MeOH or MeCN affords different products depending on the basicity and bulk of the thiolate ligand employed. Thus, the reaction with PhSH yields the thiolate bridged dimer [Ni(terpy)(SPh)2]2-6CH3OH (281), reaction with C6F5SH yields the... 

The crystal and molecular structure of the Ni11 complex of the simplest amino-thiolate ligand 2-mercaptoethylamine (aet) (454) has been determined and shows that the complex, contrary to earlier belief, has a trans configuration.1277... 

Complex [Ni(468)] is formed with Ni11 salts and the amine-thiolate ligand, or by reduction of the corresponding Schiff base complex with NaBH4-[Ni(468)] is easily deprotonated to form the dianionic complex, which is subsequently oxidized to the monoanion. On the other hand, the dianionic complex reacts with CH3I to form the fourfold methylated octahedral complex (469).1305 Since without preceding deprotonation only the S-donors are methylated, the complex with twofold amine methyla-tion must be synthesized via protection and subsequent deprotection of the S-donors.1306... 

Silver(I) trifluoromethanethiolate (AgSCF3) has been used to prepare trifluoromethyl aryl sulfides by reaction with iodide.996 A mixed silver-zinc thiolate complex [Ag4Zn2(SC6H2-Pr -2,4,6)6(OTf)2] has been prepared by reaction of AgOTf with Zn[N(TMS)2]2 in the presence of the thiol.99 Solid-state 109Ag NMR can be a sensitive environment probe for silver thiolates,998 overall for biological thiolates ligands as cysteine,999 or proteins such as metallothionein.1000,1001... 

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