Thiodiacetic acid

In rats exposed to 600 mg/m [150 ppm] 1,2-dichloroethane for 6 h or administered 150 mg/kg bw by gavage, there was no significant difference in the route of excretion of non-volatile metabolites (Reitz et al., 1982). The major urinary metabolites identified following exposure of rats by either route were thiodiacetic acid (67-68%) and thiodi-acetic acid sulfoxide (26-29%). 

Bladeren, P.J. Vermeulen, N.P. (1997) Urinary thiodiacetic acid. A selective biomarker for... 

Trichloroethane is rapidly absorbed after inhalation, oral administration and application to the skin in rodents. 1,1,2-Trichloroethane is extensively metabolized in mice given 100-200 mg/kg bw by intraperitoneal injection, 73-87 % of the dose being eliminated in the urine and 16-22% in expired air. Several urinary metabolites have been identified chloroacetic acid, S-carboxymethyl-i,-cysteine, thiodiacetic acid, 2,2-dichloroethanol and oxalic acid (lARC, 1991). 

Iodine Potassium Iodide Dodecylbenzene Tridecyibenzene Hydroquinone Propionaldehyde Methylform amide Diacetone Alcohol Isoamyl Alcohol Pentanedione (2,4-) Acetylacetone Paraldehyde Butylaldehyde Butyraldehyde Levulinic Acid Dioctyl Adipate Acetic Acid Butyl Ester Butyl Acetate Dioxane (1,4-) Dioxane Dioxane (p-) Isoamyl Acetate Thiodiacetic Acid Butyl Stearate Santoprene 201-73 Kamax T-260 Adipic Acid Ethylene Chloroformate Caprylic Acid Octanoic Acid Hexamethylenediamine Butyl Carbitol Acetate Decane Carbon Dioxide Dimethylamine Sodium Methylate Freon 114B2 Tetrachloropentane Santicizer 141 Santoprene 201-64 Ecolan Hetron 99P Calcium Hydride Triton Sulfolane Tributyl Phosphate Tributylphosphate Sodium Diacetate Methacrylonitrile... 

Thiodigiycoiic acid Thiodiacetic acid C4Hg04S 123-93-3 160.164 cry (w) 129 siH20 vsEt0H s bz... 

Thiocyclopentane-1,1-dioxide. See Sulfolane Thiocynamine. See Allylthiourea n-Thiodecyl alcohol. See 1-Decanethiol Thiodemeton. See Disulfoton 2,2 -Thiodiacetic acid. See Thiodiglycolic acid, 4,4 -Thiodianiline... 

Figure 14.1 Synthesis of EDOT from oxalic acid ester and thiodiacetic acid ester...

The earliest reports on thiopolyesters concern the syntheses of the low molecular weight polymers from the diethyl ester of thiodivaleric acid and some polymethylene diols (298), thiodiacetic acid [123-93-3] and 2,2 -thiodiethanol... 

MTO (250 mg, 1 mmol), 2,2 -thiodiacetic acid (150 mg, Immol), and PPh3 (525 mg, 2 mmol) are mixed in CH2CI2 (20 mL). The blue mixture is stirred for 10 h, layered with hexane (20 mL), and placed in a freezer at -12°C. After 24 h, a blue powder is deposited. The solid is collected by filtration, rinsed with hexane, and dried. Yield 585 mg (93%). ... 

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