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Theoretical and Methodological Principles

I have also chosen the interest domain to illustrate a simple but important methodological principle—the importance of measurement error and specificity. Measurement error and specificity saturate all psychological instruments and failure to take them into account results in theoretically misleading conclusions1. [Pg.124]

Prospective Cohort Study Prospective cohort studies are no different in principle from historical cohort studies in terms of scientific logic, the major differences being timing and methodology. The study starts with a group of apparently healthy individuals whose health and exposure are studied over a period of time. As it is possible to define in advance the information that is to be collected, prospective studies are theoretically more reliable than retrospective studies. However, long periods of observation may be required to obtain results. [Pg.1043]

This section is not intended to be a fully comprehensive presentation of all the theoretical and technical aspects of the calculation mefrioldology that has come to be known under the umbrella term of First Principles (FP). There are such reviews available and we direct the interested reader towards these throughout this Section this is not a wheel we need reinvent. It is, instead, a selective look at some of the more important aspects of the methodology, a prescription for the practitioner. We try and highlight the general features enq>loyed by almost all studies cited in this review and briefly examine strengths and weaknesses. [Pg.299]

This chapter covers the development of theoretical organic photochemistry in the writer s research group, from its primitive beginnings to its present state. A series of examples are selected from the author s research as exemplifying basic principles and computational methodology. The development of increasingly powerful theoretical and mechanistic treatments is shown with examples. [Pg.1]

The principles and methodology available for the use ofprokaryotes and eukaryotes whose cell nuclei respectively are not and are enclosed by membranes) as genetic assay systems will be summarised. Selected examples include reversion and forward-mutation assay systems. A recent theoretical analysis with limited experimental data will be presented, which describes how a plate diffusion assay may be used to study the stability of mutagenic chemicals. [Pg.251]


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Theoretical principles

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