The Physiological Systems Approach

One approach for connecting diseases to molecules is to focus on the ten fundamental physiological systems of the human body and the particular diseases associated with these systems  

Cardiovascular system (angina, myocardial infarction, arrhythmias, arterial hypertension, valvular heart disease) 

Dermatological system (erythroderma, icthyosis, Stevens-Johnson syndrome, Behcet s disease, acute blistering diseases) 

Endocrine system (Cushing s disease, Addison s disease, carcinoid syndrome, diabetes, hyperthyroidism. Grave s disease, hypothyroidism) 

Gastrointestinal system (inflammatory bowel disease [ulcerative colitis, Crohn s disease], peptic ulcer, pancreatitis, cholecystitis, hepatitis, choledocholithiasis) 

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