The New World

The isothiazole ring does not occur in nature. By far the most important synthetic isothiazole derivative is saccharin. This was the first non-carbohydrate sweetening agent to be discovered, as long ago as 1879. It is about 300 times as sweet as sucrose, and is still used in many countries as a non-nutritive sweetener. After it was found that administration of massive doses to rats caused bladder cancer, its use was banned in the New World, but the controversy continues as to whether there is any danger when it is used in small quantity. Saccharin is also used as an additive in electroplating processes (73AHC(15)233). 

Maier W. (1980). Nasal structures in Old and New World primates. In Evolutionary Biology of the New World Monkeys and Continental Drift (Ciochon A.I. and Chiarelli A.B., eds.). Karger, Basel, pp. 219-241. 

Mendoza A.S., Kuderling I., Kuhn H.J. and Kuhnel W. (1994). The vomeronasal organ of the New-world monkey Saguinus fuscicollis (Callitrichidae) — a light and transmission-electron microscopic study. Ann Anat 176, 217-222. 

The pyramids, ancient and medieval magicians, alchemists, the new world of magic... 

Darrow, Floyd L. The new world of physical discovery. Chautauqua P, 1930. 371p. 

Sometimes pollution is acceptable in small amounts. When Columbus landed in the New World there were an estimated 15,000 Indians living in the area that is now Ohio (1970 population 10,652,017). Did these Indians pollute the environment They made open tires, something that is now banned in all municipal areas, and they urinated and defecated at large. Still, since they were so few in number, the cleansing actions of the air, water and biosphere could rapidly assimilate then-wastes and no accumulating harm was done. In the strict sense of the word pollution, they did dirty the streams and anyone drinking the water shortly afterwards could contract the diseases whose infective agents were present in their wastes. However, with a little care this was unlikely, and their pollution was not considered bad. 

Brown, P. O. and Botstein, D. (1999), Exploring the new world of the genome with DNA microarrays , Nature (Genetics Supplement), 21, 33-37. 

Taken together, these advances will permit scientists and clinicians who are versed in the new world of information and computation to speed the identification of new pharmaceutical agents, eliminating products that are likely to display toxicity or poor efficacy, and reducing the formidable costs and risks associated with the current paradigms of drug discovery and development. 

Is a member of the New World hemorrhagic fever viruses normally found in Brazil. The natural reservoir is the rice rat (Oryzomys) and the virus is shed in their urine. Infection occurs after inhalation of dust contaminated with excreta from infected rats or from aerosol of animal blood or fluids. Does not produce disease in animals. This is a biosafety level 3 agent. 

For more than a century, archaeologists and others have debated the validity of proposed evidence for human occupation of the New World during the Pleistocene. The issues generally resolve themselves down to (i) can the alleged cultural materials be conclusively demonstrated to be the product of human agency and, (ii) what age assignment can be given to these items Much... 

Well, maybe. In the new world of component-based development, the successful components will be those that interoperate with many others. Each interface will be designed to couple with a range of other components and must be specified in a way that admits any component with the right behavior and excludes others. A designer aiming to meet a spec should be confident that the component works and should be able to justify that belief. 

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