The Editor Concept

Fernandez, Transformative Concepts for Drug Design Target Wrapping, 

12 Wrapper Drugs as Therapeutic Editors of Side Effects 

Dealing with problem (b) requires advanced network annotation [5, 14], The problem can be dissected by comparing protein interaction networks across tissues and placing the target protein in different interacting contexts represented in various cell types [14], In this chapter we focus on problem (b) and advocate a strategy to avert the resulting side effects. 

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The editors concept of clinical chemistry, as stated in previous volumes of this serial publication, encompasses a wide field of subjects— from the mechanism of blood coagulation to the microbiological assay of vitamins, and from the significance of trace metals in health and disease to the therapeutic application of increased gas pressure. The natural history of clinical conditions and their comparison with normal controls share one common feature, namely, the central position of some species of molecules, be they small or large, all of them the natural subject of chemical research. Hence, practical methods develop, either manual or mechanized, the results of which become increasingly more useful for the clinician in diagnosis, therapy, and prognosis. 

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