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The central dogma of molecular biology and protein synthesis

The central dogma of molecular biology and protein synthesis [Pg.167]

DNA directs its own replication and its transcription into RNA that, in turn, directs its translation into protein. tRNA is the adaptor molecule that mediates the interaction between mRNA and the encoded amino acid. [Pg.167]

Now suppose that you are a cell in possession of one copy of your genome, a small collection of DNA molecules. When you sense a round of cell division about to happen, you have two related tasks. The first is to replicate your DNA molecules exactly, so as to have two copies, one for each daughter cell. Unlike the publisher of Rowling s books, you need only one new copy, not millions, but you will need to continue to replicate the DNA molecules at each round of cell division. The second task is to translate the DNA molecule language into that of RNA and then into that of proteins. A new complement of RNA and protein molecules is required for the new cell and for the process of cell division. So the task of a cell facing cell division is not unlike that of a book publisher in some basic ways. [Pg.167]

In the last chapter, 1 developed the basics of how DNA is replicated with the help of DNA polymerases at the time of cell division. I have said nothing about the second [Pg.167]




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