Tetrazoles 1-amino-tetrazole

CN4 N N N N — 5-Amino-2-methyltetrazole 5-aminotetrazofe monohydrate sodium tetrazolate monohydrate ... [Pg.9]

However, in some cases carboxylic acid-derived groups can participate in ring fission-reclosure reactions. Thus photolysis of 1,5-disubstituted tetrazole (399) gives nitrogen and appears to involve the amino-nitrene intermediate (400), which reacts further to give (401) (77AHC(21)323). [Pg.92]

Other amino substituted isoxazoles undergo ring-opening reactions on treatment with base. Thus the amidine derivative (249) gave the triazole (250) (64TL149), while the triazene (251) on reaction with ammonia gave the tetrazole (252) (64X461). [Pg.55]

UV spectra, 5, 798 synthesis, 5, 833 thermolysis, 5, 812 Tetrazole, 5-amino-2-methyl-methylation, 5, 818 Tetrazole, 2-aryl-5-substituted quatemization, 5, 815 Tetrazole, 5-aryl-acidity, 5, 816... [Pg.853]

It should be emphasized that the correct description of the peculiar effect brought about by the presence of two or more sp -nitrogen centers within a molecule can be reproduced reliably only by high level ah initio calculations accounting for electron correlation. This conclusion is well justified by the examples of benzotriazole, 3-amino-l,2,4-triazole, and tetrazole, as described in Sections II,B,3 II,B,4 and II,B,5, respectively. [Pg.203]

Cefazaflur (58) stands out among this group of analogues because it lacks an arylamide C-7 side chain (see cephacetri 1 e for another example).Cefazaflur (58) is synthesized by reaction of 3-(1-methyl-lB[-tetrazol-5-ylthiomethylene)-7-amino-cephem-4-carboxylic acid (56) with trifluoromethylthioacetyl chloride (57). ... [Pg.213]

Amino-3-(1 -methyl-1 H-tetrazol-5-yI-thiomethyI)-3-cephem-4-carboxylic acid... [Pg.261]

Chemical Name (6R-trans)-3-([(5-methyl-1,3,4-thiadiazol-2-yl)thio] methyl)-8-oxo-7-([(1-H-tetrazol-1 -yl)acetyl] amino)-5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylic acid sodium salt... [Pg.263]

Aminosodium salt and acylated with 1 H-tetrazole-1 -acetyl chloride. The acetoxy group is then displaced by reaction with 5-methyl-1,3-4-thi-adiazole-2-thiol in buffer solution. The product acid is converted to the sodium salt by NaHCOa. [Pg.264]

Compound 961 has been converted into 3-amino-6-azido-5(2//)[ 1,2,4]tri-azinone 1041, which was employed in a study of azide-tetrazole equilibrium affording 6-amino-8(5//)tetrazolo[5,1-/][1,2,4]triazinone 1042 (79JHC555) (Scheme 196). [Pg.153]

The diazotization of heteroaromatic amines is basically analogous to that of aromatic amines. Among the five-membered systems the amino-azoles (pyrroles, diazoles, triazoles, tetrazoles, oxazoles, isooxazoles, thia-, selena-, and dithiazoles) have all been diazotized. In general, diazotization in dilute mineral acid is possible, but diazotization in concentrated sulfuric acid (nitrosylsulfuric acid, see Sec. 2.2) or in organic solvents using an ester of nitrous acid (ethyl or isopentyl nitrite) is often preferable. Amino derivatives of aromatic heterocycles without ring nitrogen (furan and thiophene) can also be diazotized. [Pg.16]

CN [6R-[6a,7p(/J )]]-7-[(hydroxyphenylacetyl)amino]-3-[[(l-methyl-l//-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-l-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid... [Pg.373]

R)-amino-3-(1-methyl-1 H-tetrazol-5-ylthio-methyl)-3-cephem-4-corboxylic ocid (cf. cefomondole synthesis)... [Pg.386]

CN (6/f-/rani)-7-[[(2-amino-4-thiazolyl)acetyl]amino]-3-[[[ 1 -[2-(dimethylamino)ethyl]-1 //-tetrazol-5-... [Pg.391]

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