Tetrahydro-B-carboline

Tryptamine, with glyoxylic acid to give 1,2,3,4-tetrahydro-B-carboline, 51, 136... [Pg.136]

HARMAN, 6-METHOXY-1,2,3,4-TETRAHYDRO b-CARBOLINE, 6-METHOXY-1 -METHYL-1, 2,3,4-TETRAHYDRO 6-METHOXY-1,2,3,4-TETRAHYDROHARMAN 10-METHOXY-3,4,5,6-TETRAHYDROHARMAN 6-METHOXY-1 -METHYL-1,2,3,4-TETRAHYDRO-b-CARBOLINE 1-METHYLPINOLINE ADRENOGLOMERULOTROPIN ALDOSTERONE-STIMULATING HORMONE MCISAAC S COMPOUND... [Pg.218]

One of the most valuable and widely used applications of C=N bond hydrogenation is in the field of reductive alkylation, in which an aldehyde or ketone is condensed with an amine and reduced in situ with an appropriate catalyst to give a substituted product. This very valuable reaction has most notably been employed for the racemic synthesis of amino acids from a-ketoesters and acids. This type of reduction can be very powerful, as illustrated by the synthesis of tetrahydro-b-carbolines 64 (76% yield) by the reductive coupling of 65 and 66 under conditions of 1 atm of hydrogen and palladium on carbon catalyst277. [Pg.828]

N. Ide, M. Ichikawa, K. Ryu, K. Ogasawara, J. Yoshida, S. Yoshida, T. Sasaoka, S.-I. Sumi, and H. Sumiyoshi, Antioxidants in processed garlic. II. Tetrahydro-b-carboline derivatives identified in aged garlic extract, in G, 2002, 449 150. [Pg.173]

PTCC = l-(2 -Pyrrolidinethione-3 -yl)-1,2,3,4-tetrahydro-b-carboline-3-carboxylic acid. [Pg.1106]

Kuehne ME, Roland DM et al (1978) Studies in biomimetic alkaloid syntheses. 2. Synthesis of vincadifformine from tetrahydro-b-carboline through a secodine intermediate. J Org... [Pg.393]

SCHEME 16.33. EnantioselectivePictet-Spengler reaction leading to tetrahydro-b-carbolines. [Pg.573]

Treatment of 4-oxo-tetrahydro-B-carboline with hydrazine gave... [Pg.233]

Yao K, Zhao M, Zhang X, Wang Y, Li L, Zheng M, Peng S (2011) A class of oral N-[(lS,3S)-l-methyl-l,2,3,4-tetrahydro-b-carboline-3-carbonyl]- NO-(amino-acid-acyl) hydrazine Discovery, synthesis, in vitro anti-platelet aggregation/in vivo anti-thrombotic evaluation and 3D QSAR analysis. Eur J Med Chem 46 3237-3249... [Pg.572]

Facile Synthesis of 1,2,3,4-Tetrahydro-b-carbolines by One-Pot Domino Three-Component Indole formation and Nucleophihc Cyclization Yusuke Ohta, Shinya Oishi, Nobutaka Fujii and Hiroaki Ohno Org. Lett. 2009, 11, 1979-1982. Reproduced with permission... [Pg.6]

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