Tetrabromodiphenyl

The position number assignments in the table are for convenience and are arbitrarily fixed to the position numbering of 2,2, 4,4 -tetrabromodiphenyl ether. 

The mixture of deca-BDE is composed almost exclusively of deca-BDE (BDE-209), with a rate of 97% or more and by 3% or less of nonabromodiphenyl ethers (nona-BDEs) and octa-BDEs. On the contrary, the commercial octa-BDE mixture usually contains between 10% and 12% hexabromodiphenyl ethers (hexa-BDEs), 44% of heptabromodiphenyl ethers (hepta-BDEs), between 31% and 35% of octa-BDEs, between 10% and 11% of nona-BDEs and <1% of deca-BDE [4]. The two compounds with a higher proportion in this mixture are, in first place, BDE-183 (2,2, 3,4,4, 5, 6-hepta-BDE) and then the BDE-153 (2,2, 4,4, 5,5 -hexa-BDE). In addition, the penta-BDE mixture, commercially known as DE-71, is primarily composed by tetrabromodiphenyl ethers (tetra-BDEs) (24—38%), penta-BDEs (50-60%) and hexa-BDEs (4-8%) being BDE-99 (2,2, 4,4, 5-penta-BDE) and BDE-47 (2,2, 4,4 -tetra-BDE) the main compounds of the mixture. Figure 1 shows different structures belonging to the three PBDE mixtures described. 

DeBDE=Decabromodiphenyl ether HpBDE=Heptabromodiphenyl ether HxBDE=Hexabromodiphenyl ether NoBDE=Nonabromodiphenyl ether OcBDE=Octabromodiphenyl ether PBDE=Polybrominated diphenyl ether PeBDE=Pentabromodiphenyl ether TeBDE=Tetrabromodiphenyl ether TrBDE=Tribromodiphenyl ether... 

Tolybrominated biphenyls category includes decabromobiphenyl (CAS 13654-09-6) decabromodiphenyl ether (CAS 1163-19-5) hexabromobiphenyl (CAS 59080-40-9) hexabromo-1,1 -biphenyl (CAS 36355-01-8) hexabromodiphenyl ether (CAS 36483-60-0) nonabromodiphenyl ether (CAS 63936-56-1) octabromobiphenyl (CAS 27858-07-7) octabromobiphenyl (CAS 61288-13-9) octabromodiphenyl ether (CAS 32536-52-0) p-bromodiphenyl ether (CAS 101-55-3) p,p -dibromodiphenyl ether (CAS 2050-47-7) pentabromodiphenyl ether (CAS 32534-81-9) polybrominated biphenyl (CAS 59536-65-1) polybrominated biphenyl mixture (CAS 67774-32-7) tetrabromodiphenyl ether (CAS 40088-47-9) and tri bromodiphenyl ether (CAS 49690-94-0). 

Kato Y, Yumoto S, Nagano Y, et al. 2000. 3-Mctliylsulfonyl-2,2, 4, 5-tetrabromobiphcnyl. a metabolite of 2,2, 4, 5-tetrabromodiphenyl induces CYP2B1/2 in rats. Organohalogen Compounds 49 209-212. 

Anjaneyulu V, Nageswara Rao K, Radhika P, Muralikrishna M, Connolly JD (1996) A New Tetrabromodiphenyl Ether from the Sponge Dysidea herbacea of the Indian Ocean. Indian J Chem 35B 89... 

PBDEs are commercially available as three products penta-, octa-, and deca-BDE. All of these products are mixtures of several congeners. The compositions of these three products, as measured in our laboratory at Indiana University, are given in Table 4. The penta-product contains primarily 2,2/,4,4/-tetrabromodiphenyl ether (BDE-47), 2,2, 4,4, 5-pentabromodiphenyl ether (BDE-99), and 2,2, 4,4, 6-pentabromodiphcnyl ether (BDE-100) in a ratio of about 7 10 2. The octa-product contains primarily 2,2, 3,4,4, 5, 6-heptabromodiphenyl ether (BDE-183), 2,2, 3,3, 4,4, 5,6 -... 

Lema, S. C., Schultz, I. R., Scholz, N. L., Incardona, J. R, Swanson, R. (2007) Neural defects and cardiac arrhythmia in fish larvae following embryonic exposure to 2,2, 4,4 -tetrabromodiphenyl ether (RBDE 47). Aquat. Toxicol, 82 296-307. 

Reported octanol-air partition coefficients of 2,3, 4,4 -tetrabromodiphenyl ether (PBDE 66) at various temperatures... 

---