Testosterone-related disorders

Finally, signs of precocious puberty have been reported in ASD subjects (Tordjman and Ferrari, 1992) and elevated rates of testosterone-related disorders such as polycystic ovary syndrome, irregular menstrual cycle, dysmenorrhoea, hirsutism, severe acne, epilepsy, tomboyism, and bisexuality or asexuality have been found in women with autism spectrum conditions (Ingudomnukul et al., 2007), suggesting post-natal hormone abnormalities in testosterone production or sensitivity, though the relationship between FT and post-natal testosterone levels has not been clarified yet. 

Ingudomnukul E, Baron-Cohen S, Wheelwright S, Knickmeyer R (2007) Elevated rates of testosterone-related disorders in women with autism spectrum conditions. Horm Behav 51 597-604. 

Rl 1. Rosmond, R., and Bjorntorp, R, The interactions between hypothalamic-pituitary-adrenal axis activity, testosterone, insulin-like growth factor I and abdominal obesity with metabolism and blood pressure. Int. J. Obes. Relat. Metab. Disord. 22, 1184—1196 (1998). 

De Pergola G, Pannacciulli N, Ciccone M, et al. Free testosterone plasma levels are negatively associated with the intima-media thickness of the common carotid artery in overweight and obese glucose-tolerant young adult men. IntJ Obes Relat Metab Disord 2003 27 803-807. 

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