Tertiary screen

The further study is whatever you want it to be bearing in mind that the tertiary screen is designed to allow sound, decisions to be made on the selection of compounds for transition into field development pro-... 

Optimized leads identified in the secondary screening phase of a HT-R D program are then taken to the tertiary screening phase to generate commercial development candidates. This usually takes the form of a conventional mini- or pilot-plant. 

Fig. 1.5 Timeline showing progress in primary, secondary, and tertiary screening experiments.

Tertiary screening or traditional laboratory-scale reactors are used to evaluate the secondary leads. Depending on the richness of the data generated in the secondary screen, the tertiary screen may be focused on more complete analysis, or may be focused on other aspects of catalyst performance such as lifetime, susceptibility to poisons, or hydrodynamics. 

To ensure the clear identification of good catalysts amongst very large numbers of formulations, a three-step approach of primary, secondary, and tertiary screening is typically applied (Figure 3). 

Potyrailo, R. A. Morris, W. G. Wroczynski, R. J., Multifunctional sensor system for high-throughput primary, secondary, and tertiary screening of combinatorially developed materials, Rev. Sci. Instrum. 2004, 75, 2177-2186... 

Blurring the Lines between Primary, Secondary and Tertiary Screening... 

Figure 3.5 Multi-tiered screening process. The path from primary to tertiary screening focuses the final sequence that gives the best combination of purity and yield in purification...

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