Tertiary amines nomenclature

Secondary and tertiary amines, which have two and three substituents on nitrogen, commonly are named as N-substituted amines. As for substituted amides, N is included to indicate that the substituent is on the nitrogen atom unless there is no ambiguity as to where the substituent is located. Systematic nomenclature of secondary and tertiary amines is related to the systematic ether nomenclature discussed in Section 7-3 ... 

When naming the secondary and tertiary amines, the smaller group is written first and the other groups are added before the word -amine . If the groups are the same, the di- or tri- prefixes are used. In common nomenclature we use the locant N to designate substituents attached to a nitrogen atom. 

Information about lUPAC nomenclature of secondary and tertiary amines... 

V te will not introduce the nomenclature for secondary and tertiary amines and amides in this text... 

In common nomenclature, amines are described as alkylamines. The common name of a primary amine results from naming the alkyl group bonded to the amino group (—NH2) and adding the suffix -amine. The entire name is written as one word. The common name for a secondary or tertiary amine is obtained by listing the alkyl groups alphabetically. When two or more identical alkyl groups are present, the prefixes di- and tri- are used. 

The nomenclature of amines is exceptional. By very long custom radical names may be attached to the ending amine, as in ethylamine but it is equally correct to add amine to the parent name, as indicated in Table 4, giving names such as phenanthren-1-amine, quinolin-8-amine, or even ethanamine. The latter practice is often reserved for more complex cases but that is not a necessary limitation. The same alternatives exist for ammonium salts. Secondary and tertiary amines are treated as substitution products of the most complex constituent primary amine, with N- prefixes when substitution elsewhere might be reasonable, as in triethylamine, dimethylamine,... 

Secondary and tertiary amines are in most cases still named radicofunc-tionally, in a manner that can easily be transformed into a substitutive naming mode based on the parent hydride name azane. Within the boundaries of conventional substitutive nomenclature, amines of that sort are interpreted as products of N-substitution of the most serior primary amine present. 

The primary (1), secondary (2 ), tertiary (3) and quaternary (4) nomenclature is used in a number of situations to define a carbon centre, or to define functional groups like alcohols, halides, amines and amides. Identifying functional groups in this way can be important because the properties and reactivities of these groups vary depending on whether they are primary, secondary, tertiary or quaternary. 

The term enamine is used mainly for classifications of the functional group as an ensemble, but individual compounds are termed with respect to the parent compound usually as amino substituted olefins, i.e. tertiary enamines as (N,iV-dialkylamino)alkenes. The correct IUPAC nomenclature for tertiary enamines is dialkylalkenylamines, i.e. the basic compound in this case is the amine not the alkene. The difference may be demonstrated for two examples 73 is in the first notation l-iV-methylanilino-2-methyl-propene and, in IUPAC notation, iV-methyl-jV-(2-methyl-l-propenyl)aniline. Correspondingly 74 is usually called 2-methyl- 1-pyrrolidinopropene but in IUPAC notation it is jV-(2-methyl-l-propenyl)pyrrolidine. 

Nitrogen mustards are tertiary hw(2-chloroethyl)amines with vesicant activity (NDRC, 1946). AH are active alkylating agents. The nomenclature, chemical and physical properties of HNl, HN2, and HN3 are summarized in Tables 8.3 and 8.4. Due to their toxicity and various... 

Fig. 3.11 Structures of the tripodal complexes. The p, s, and t nomenclature for [Co(tren)(NH3)X]2+ ions denote primary, secondary and tertiary N centres respectively, trans to the in plane ammine (group being substituted) and anti and syn denote the relationship of the methyl substituent to this amine.

In common nomenclature most primary amines are named as alkylamines. In systematic nomenclature (blue names in parentheses below) they are named by adding the suffix -amine to the name of the chain or ring system to which the NH2 group is attached with replacement of the final -e. Amines are classified as being primary (1°), secondary (2 ), or tertiary (3 ) on the basis of the number of organic groups attached to the nitrogen (Section 2.8). 

The nomenclature of amines differs from that of the alcohols. The des nations primary, secondary, and tertiary refer to the number of substituents on the ammonia nitrogen ... 

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