Target Organ Systemic Toxicity Following Single Exposure

Does the mixture as a whole have data/information to evaluate specific target organ systemic toxicity following single exposure ... 

OECD has published a document on a Harmonised integrated classification system for human health and environmental hazards of chemical substances and mixtures (OECD 2001b). Chapter 2.1 addresses a harmonized system for the classification of chemicals which cause acute toxicity, and Chapter 2.8 addresses the chemicals which cause specific target organ oriented systemic toxicity following a single exposure. 

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