Takamine, Jokichi

Jokichi Takamine (1854-1922) went to the University of Glasgow, and then, to the United States to investigate the phosphatic manure, and he established the first company of phosphatic manure in Japan. He produced Takadiastase, a digestive agent containing various digestive enzymes, ribonuclease and cellulase. Amylase was extracted from Takadiastase. In a narrow sense, Takadiastase is one of the carboxyoroteases. He discovered in 1900. 

Jokichi Takamine (1854-1922), Japanese-Ameri-can chemist, and T. B. Aldrich first isolate epinephrine from the adrenal gland. Later known by the trade name Adrenalin, it is eventually identified as a neurotransmitter. 

In 1890, the Japanese chemist Jokichi Takamine had introduced a fermentation process in the United States by which an enzyme blend was produced. This takadias-tase catalyzed starch and protein hydrolysis. Some years later in 1913, Boidin and Effront discovered the bacillus subtilis" that produced an a-amylase stable under heat. This enzyme was used to desize cloth and later in the sugar fermentation process. 

Jokichi Takamine (1854-1922). It was his assistant Keizo Uenaka who got the crystals, but Takamine filed the patent application and claimed the fame. 

Japanese chemist Jokichi Takamine (1854-1922) isolates adrenaline (the first hormone to be isolated). 

On the other hand, Nagayoshi Nagai (1845—1929) et al. isolated ephed-rine, which will be discussed in Chapter 16.1. Also, Jokichi Takamine (1854-1922) succeeded in the isolation of adrenaline (epinephrine), and Umetaro Suzuki (1874-1943) discovered oryzanin. 

Japanese-bom scientist Jokichi Takamine developed the commercial nse of mold-derived enzymes and introduced these fungal products to industry. Takamine, the Japanese father of American biotechnology , brought a modification of the koji process to the United States in the late nineteenth century (Bennett, 1985 Machida et al., 2008). He believed koji-derived amylolytic enzymes conld revolutionize the American distillery industry. His method involved growing A. oryzae on steamed bran and using aqueous... 

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