Tablet filling stages

The staged release and improved appearance from the layered tablet are also possible. In the preparation of a tablet within a tablet, a special tableting machine is required to place the intended core tablet precisely within the die, which already contains some of the coating formulation to surround the fill materials. This multilayered tablet or tablet within a tablet is also useful to get the modified release, either immediately or in a sustained manner. 

FIGURE 4 Stages of tableting process (a) filling (b) compression (c) ejection. 

The manufacturing process of tablets principally consists of three stages filling the die with the powder, compressing the powder, and ejecting the tablet from the die. 

The process of tablet compression is divided into three stages filling, compression, and ejection of the tablet (see Figure 1). 

Precompression and Main Compression Rollers. After die fill and scrape-off, the punches rotate to the precompression station where an initial force is applied to the compact. The tablet is frequently partially formed during the precompression stage. Subsequently, the upper and lower punches move together under the main compression rollers where the final tablet is formed. The main compression roller is usually larger than the precompression roller. However, latest advances suggest that similar sizes for precompression and main compression rollers with the ability to apply similar loads may result in optimal tablet formation. The compression rollers are made of premium tool steels and are surface hardened. 

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