Tablet compression molding

Tablets, hypodermic Molded tablet triturates intended to be dissolved in water to make a solution to be injected parenterally. The usual weight of hypodermic tablets is about 0.03 g, which distinguishes them from ordinary tablet triturates that weigh about 0.06 g. Formerly prepared extemporaneously by pharmacists, modern compressed hypodermic tablets are not intended to be sterile, although they are manufactured under strict conditions as a precaution against contamination (see Triturates, tablet) ...

Tablets, solution Molded or compressed tablets containing large amounts of potent substances not intended for administration, but rather as a...

Compression molding is a process in which tablets are prepared from soluble ingredients such as sugars by compressing a powder mixture previously moistened with solvent (usually ethanol or water) into mold plates to form a wetted massJ ... 

Many processes consist of multiple streams, such as multiple-head fillers for powder fills or multicavity molds for tablet compression. Each stream must be considered a separate process. There are two general situations ... 

LSD has been dispersed in numerous forms. Delysid (LSD-25) from Sandoz was distributed in ampules and also tablets containing 100 rg.. LSD that appeared outside of research circles was usually triturated (dosed) on sugar cubes and in tablet form (both as compressed tablets and molded tablets) of many sizes and colors. LSD that is dispersed into films (clearlight, window pane) of gelatin, agarose or cellulose also appears in a variety of colors and shapes. The most common form of LSD appears in blotter paper form. 

Preform v. (1) To make plastic molding powders into pellets, tablets, or biscuits of known mass that facilitate accuracy in compression molding. (2) To prepare by hand cutting of reinforcing cloth or mat, or by blowing chopped fibers onto a contoured screen, the reinforcement for a fiber-reinforced molded object. The reinforcement, which has a shape close to that of the final molded object, is placed into or onto the mold along with the required amount of resin, then wet out and cured. 

The pharmaceutical industry has been using lactose for many years because its properties that aid flow characteristics and tablet or pill formation. The drug is distributed uniformly in lactose powder, which is easily molded or compressed into tablets. These have good dispers-... 

About 2500/minute for automatic equipment Molded tablets are generally softer and more readily soluble than compressed tablets. 9... 

Preform A compressed tablet or biscuit of plastic composition used for efficiency in handling and accuracy in weighing materials, (v.) To make plastic molding powder into pellets or tablets. 

Lozenges can be made by molding or by compression at high pressures, often following wet granulation, resulting in a mechanically strong tablet that can dissolve... 

Tablets Dosage forms prepared by molding or compressing medicinal substances in dies. Tablets vary widely in shape, the most common form being discoid, and range from 0.06 to 0.60 g in weight. Jean de Renou applied the Latin word tabella to a special type of troche in 1608 Burroughs Wellcome Company coined the term tablet in 1878 to refer to its brand...

In general, the manufacturing process used for the majority of these tablets are the same as those used for humans and are discussed elsewhere (chap. 13, vol. 1). Direct compression and granulation (wet, dry) are both used. Chewable tablets can also be made by these methods or sometimes are molded via excursion and cut into appropriate sizes. The terms chewable tablets and treats are sometimes confusing. One way to classify is to state that chewable tablets that are made by direct or granulation processes are then called tablets. This would be similar to the mannitol-based chewable tablets prevalent for humans. The term treat is used for the more soft tablets that are produced via extrusion or cast molding. 

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