Synthesis of organosilicon compounds

Much of the early work on the synthesis of organosilicon compounds was based on reactions between Grignard reagents and silicon halides (and to a lesser extent on silicate esters), and much effort was devoted to optimizing stepwise reactions  

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Peroxy Compounds of Transition Metals J. A. Connor and E. A. V. Ebsworth The Direct Synthesis of Organosilicon Compounds J. J. Zuckerman... 

Organosilicon compounds are widely used in our daily life as oil, grease, rubbers, cosmetics, medicinal chemicals, etc. However, these compounds are not naturally occurring substances but artificially produced ones (for reviews of organosilicon chemistry, see [59-64]). Hydrosilylation reactions catalyzed by a transition-metal catalyst are one of the most powerful tools for the synthesis of organosilicon compounds. Reaction of an unsaturated C-C bond such as alkynes or alkenes with hydrosilane affords a vinyl- or alkylsilane, respectively (Scheme 16). 

Hydrosilylation, the addition of a silicon-hydrogen bond to multiple bonds, is a valuable laboratory and industrial process in the synthesis of organosilicon compounds. The addition to carbon-carbon multiple bonds can be accomplished as a radical process initiated by ultraviolet (UV) light, y irradiation, or peroxides. Since the discovery in the 1950s that chloroplatinic acid is a good catalyst to promote the addition, metal-catalyzed transformations have become the commonly used hydrosi-... 

Yoo, Bok Ryul, and Jung, II Nam, Synthesis of Organosilicon Compounds by New Direct... 

The reactions of silicon halides with organomagnesium or organolithium compounds for the synthesis of organosilicon compounds are oversimplified in Eqs. (3) and (4). If several reactive groups are attached to the silicon atom, as in C2H5SiCl3, the reaction cannot be controlled so as to yield a particular substitution product, since all possible substitutions will occur simultaneously. All that can be done is to favor the yield of the desired compound by manipulation of reaction conditions. 

Synthesis of organosilicon compounds from organomagnesium compounds... 

A variety of reactions generate new silicon-carbon bonds, although most of them are not utilized in the systematic synthesis of organosilicon compounds. Representative and interesting examples are shown in the following. 

The addition reaction of hydrosilanes to alkenes and alkynes is called hydrosilylation, a reaction which was discovered when a mixture of 1-octene and trichlorosilane was heated in the presence of diacetyl peroxide. This reaction is particularly useful for the synthesis of organosilicon compounds. Since then, a variety of catalysts and conditions have been reported. Characteristic features of the reaction are discussed in this chapter. 

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