Synaptic mechanism

Kaba H. and Nakanishi S. (1995). Synaptic mechanisms of olfactory recognition memory. Int Rev Neurosci 6, 125-141. 

Mansvelder, H.D., Keath, J.R., McGehee, D.S. Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas. Neuron. 33 905, 2002. 

Pidoplichko, V.I., Noguchi, J., Areola, O.O. et al. Nicotinic cholinergic synaptic mechanisms in the ventral tegmental area contribute to nicotine addiction. Learn. Mem. 11 60, 2004. 

What are the precise synaptic mechanisms that mediate tolerance and cross tolerance to LSD Are they different than the basic processes that mediate the acute actions of these drugs ... 

Mansvelder HD, McGehee DS (2002) Cellular and synaptic mechanisms of nicotine addiction. J Neurobiol 53 606-617... 

Goodwin FK, Murphy DL, Dunner DL, et al Dthium response in unipolar versus bipolar depression. Am J Psychiatry 129 76-79, 1972 Goodwin GM, DeSouza RJ, Wood AJ, et al TJie enhancement by lithium of the 5-HTlA mediated serotonin syndrome produced by 8-OH-DPAT in the rat evidence for a post-synaptic mechanism. Psychopharmacology 90 488-493, 1986a Goodwin GM, DeSouza RJ, Wood AJ, et al Lithium decreases 5-HTlA and 5-HT2 receptor and alpha-2 adrenoceptor mediated function in mice. Psychopharmacology 90 482-487, 1986b... 

Mendelson SD, Quartermain D, Francisco T, et al S-HTj agonists induce anterograde amnesia in mice through a post synaptic mechanism. Eur J Pharmacol 236 177-182, 1993... 

As indicated above, detection of evoked quantal responses (either through minimal stimulation or paired recordings) provides a suitable setting to determine neurotransmitter release probability and alterations in rate of vesicle fusion. However, in synapses with multiple release sites, such as the calyx of Held, isolation of evoked quantal responses is nearly impossible and truly quantal release is hard to detect except in the case of spontaneous neurotransmission. Therefore, under these conditions, the rate of synaptic vesicle fusion can be determined by deconvolution of synaptic currents with the quantal unitary current. This approach is valid only when the synaptic current can be assumed to result from the convolution between a quantal current and quantal release rates. This assumption is not valid in cases where post-synaptic mechanisms, such as receptor saturation and desensitization, alter quantal events and thus shape synaptic responses during repetitive stimulation (Neher and Sakaba, 2001). 

Bartos M, Vida I, Jonas P. 2007. Synaptic mechanisms of synchronized gamma oscillations in inhibitory intemeuron networks. Nat Rev Neurosci 8 45-56. 

Ungerstedt U, Herrera-Marschitz M, Stahle L, Zetterstrom T (1982) Models for studying the synaptic mechanisms correlative measurements of transmitter release and drug altered behaviour. In Spiegelstein MY, Levy A (Eds), Behavioural Models and the Analysis of Drug Action, pp. 57-70. Elsevier, Amsterdam. 

Mansvelder HD, Keath JR, McGehee DS (2002) Synaptic mechanisms underlie nicotine-induced exdtability of brain reward areas. Neuron 33 905-919 Mansvelder HD, McGehee DS (2000) Long-term potentiation of excitatory inputs to brain reward areas by nicotine. Neuron 27 349-357... 

The numerical diversity of Na channel genes and their variable expression patterns increase the probabihty that the anticipated channel subunit mutations will generate multiple CNS excitability profiles finked to distinct clinical seizure types. Each of these selective excitability increases in specific axonal pathways may act to synchronize large neuronal populations by synaptic or non-synaptic mechanisms. This review considers the anatomical aspects of Na channel involvement in epileptogenesis, namely, how the site of expression of the Na channel gene, both within the neuron and within specific brain pathways, acts as an important phenotypic determinant of the disorder. 

Thesleff, S. 1989. Botulinal neurotoxins as tools in studies of synaptic mechanisms. Q. J. Exp. Physiol. 74 1003-1017. 

The responses of the mitral/granule system to single or paired orthodromic and antidromic volleys are well understood. But, the function of this reciprocal synaptic mechanism in processing odor evoked activity depends on its response to spatially and temporally patterned activity in the olfactory nerve. 

Mifflin SW, Felder RB (1990) Synaptic mechanisms regulating cardiovascular afferent inputs to solitary tract nucleus. Am J Physiol 259 H653-H661 Mochizuki H, Shimizu T, Morikawa A, Kuroume T (1995) Inhaled diuretics attenuate acid-induced cough in children with asthma. Chest 107 413 17 Monnet FP (2005) Sigma-1 receptor as regulator of neuronal intracellular Ca2-l- Clinical and therapeutic relevance. Biol Cell 97 873-883... 

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