Sweating, withdrawal symptoms

The abstinence syndrome (synonym, withdrawal symptom) is observed after withdrawal of a dtug to which a person is addicted. For example, the abstinence syndrome after alcohol withdrawal is characterized by tremor, nausea, tachycardia, sweating and sometimes hallucinations. 

The initial dose of SSRI is similar to that used in depression. Patients should be titrated as tolerated to response. Many patients will require maximum recommended daily doses. Patients with comorbid panic disorder should be started on lower doses (Table 37-4). When discontinuing SSRIs, the dose should be tapered slowly to avoid withdrawal symptoms, with the possible exception of fluoxetine. Relapse rates may be as high as 50%, and patients should be monitored closely for several weeks.58 Side effects of SSRIs in SAD patients are similar to those seen in depression and most commonly include nausea, sexual dysfunction, somnolence, and sweating. 

Tolerance develops to many of A -THC s effects in heavy marijuana users. Although chronic cannabis use does not result in severe withdrawal symptoms, numerous case reports attest to development of dependence in subjects taking high doses of THC for several weeks. The most prominent symptoms were irritability and restlessness others included insomnia, anorexia, increased sweating, and mild nausea. Cessation of mild or moderate use of marijuana, however, does not produce a withdrawal syndrome. 

Do not discontinue oral drug abruptly or withdrawal symptoms may occur (anxiety, increased BP, headache, insomnia, increased pulse, tremors, nausea, sweating)... 

Tolerance to inhalants can develop with frequent use, and withdrawal symptoms include sleep disturbance, irritability, jitteriness, sweating, nausea and vomiting, fast heart rate, and hallucinations or delusions. Withdrawal can last one month or longer, and the relapse rate is high. 

Despite their ability to keep us awake, stimulants can produce unwanted side effects, such as anxiety, muscle tremor (the shakes ), sweating, hyperthermia, insomnia, and headaches, especially when taken in larger than recommended quantities. In addition, some stimulants are addictive when taken repeatedly, and when their use is stopped suddenly, withdrawal symptoms can occur that include depression, fatigue, irritability, nausea, and headaches. 

The toxic chemicals in inhalants are stored in fatty tissue in the body for weeks. Thus, when long-term abusers attempt to quit, they may develop withdrawal symptoms several hours to a few days afterward. The Office of National Drug Control Policy and the American Academy of Pediatrics list these common withdrawal symptoms hand tremors, excessive sweating, constant... 

However, if the patient has also been abusing other inhalants, the detoxification period could conceivably take up to 40 days, depending on the chemicals involved. Withdrawal symptoms in inhalant abusers may include nausea, vomiting, muscle pain and cramping, chills and sweats, irritability, tremors, headaches, and hallucinations. Depending on the severity of the symptoms and the patient s physical condition, the controlled environment of a residential setting may be preferred for the detox period. 

PCP intoxication typically produces miosis, nystagmus, hypertension, tachycardia, salivation, flushing, sweating, ataxia, and CNS stimulation or depression. Overdose of PCP is dangerous, as the user becomes violent and emergency treatment is required. It is necessary to keep the user calm and not leave him alone. Withdrawal symptoms of PCP are tremor, seizures, diarrhea, piloerection, and vocalizations. 

Alcohol Withdrawal Syndrome Withdrawal symptoms of alcohol include alcohol craving, tremor, irritability, nausea, sleep disturbance, tachycardia, hypertension, sweating, seizures 12 to 48 hours after last drinking, severe agitation, confusion, and dilated pupils. 

Barbiturate overdose may be treated with gastric lavage and oral administration of activated charcoal. Supportive therapy of cardiovascular, respiratory, and renal function also should be provided. Coadministration of alcohol and barbiturates may increase the sedative effect of chloral hydrate. Long-term use of barbiturates leads to dependence. Sudden discontinuation of an antipsychotic drug may cause withdrawal symptoms such as nausea, vomiting, anorexia, diarrhea, rhinorrhea, sweating, insomnia, restlessness, and vertigo.151... 

A 27-year-old man developed withdrawal symptoms (dizziness, nausea, vomiting, sweating, anxiety, insomnia, and restlessness) after nefazodone was abruptly withdrawn after 1 month (15). 

There is no question that dependence on narcotics, with physical components, can develop quickly with repeated administration. When medical patients receive morphine by injection every four hours, some degree of dependence can occur in as few as twenty-four hours. If the drug is stopped even after a short period of use, mild withdrawal symptoms may occur — including sweating, nausea, weakness, headache, restlessness, and increased sensitivity to pain. 

Withdrawal symptoms resembling cholinergic rebound (nausea, tremor, and sweating) have been described after long-term brompheniramine treatment (1). 

Three cases of withdrawal symptoms after abrupt withdrawal of high-dose gabapentin have been reported in adults with psychiatric conditions (41). The patients were restless and anxious, with sweating and tachycardia. The symptoms improved after gabapentin was reintroduced. 

Tolerance to the effects of methadone develops with repeated doses, but more slowly than is true for morphine. Likewise, withdrawal develops more slowly and is generally less intense but more prolonged than morphine withdrawal. Withdrawal symptoms include weakness, anxiety, insomnia, abdominal discomfort, sweating, and hot and cold flashes. ... 

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