Sutherland, Edwin

Sutherland, Edwin H., and Donald R. Cressey. Criminology. Philadelphia Lippincott, 1978. This is an updated edition of the first recognized textbook in the field, which defined the discipline and articulated basic concepts and methodologies for the study of crime and criminals. 

The Coris found that the interconversion of phosphor-ylases a and b is catalyzed by another enzyme, and subsequent work by Earl Sutherland showed that this process is under hormonal control. In muscle, conversion of phosphorylase b to a is stimulated by epinephrine in liver, it is stimulated by both epinephrine and the pancreatic hormone glucagon. The structural basis for the difference between the two forms of phosphorylase remained unknown until the late 1950s, when Edwin Krebs and Edmund Fischer showed that phosphorylase a has a phosphate on serine 14. This phosphate is absent in the b form of the enzyme. Krebs and Fischer also showed that the kinase that catalyzes the addition of the phosphate is itself regulated by a phosphorylation catalyzed by another enzyme, the cAMP-dependent protein kinase ... 

Cyclic AMP (= cAMP) (cyclic nucleotide) Earl Sutherland (USA, Nobel Prize, Medicine, 1971, cAMP as second messenger) Edwin Krebs Edmond Fischer (USA, Nobel Prize, Medicine, 1992, PKA)... 

Edwin H. Sutherland, The Diffusion of the Sexual Psychopath Laws , American Journal of Sociology 56 (September 1950), p. 143. 

---