Susceptibility genes

Turecki, G., Grof, R, Grof, E. etal. (2001). Mapping susceptibility genes for bipolar disorder a pharmacogenetic approach based on excellent response to lithium. Mol. Psychiatry, 6, 570-8. 

Cox NJ, Bell GI. Disease associations chance, artifact or susceptibility genes Diabetes 1989 38 947-950. 

Peterson LE, Barnholtz JS, Page GP, King TM, de Andrade M, Amos Cl. A genome-wide search for susceptibility genes linked to alcohol dependence. Genet Epidemiol 1999 17(Suppl 1] S295—300. 

One of the most heritable of all psychiatric disorders likely multiple susceptibility genes of small effect... 

Straub RE et al. Susceptibility genes for nicotine dependence a genome scan and followup in an independent sample suggest that regions on chromosomes 2, 4, 10, 16, 17 and 18 merit further study. 

Maraganore, D. M.,Lesnick,T. G.,Elbaz, A. etal. UCHL1 is a Parkinson s disease susceptibility gene. Ann. Neurol. 55 512-521,2004. 

Meta-analysis of the 20 genome-wide scans for linkage to schizophrenia has identified loci on 16 of the auto-somes at which susceptibility genes are likely located[5]. Thus far, there is no evidence for autosomal dominant/ recessive Mendelian-like genes that would account for schizophrenia. Potential risk genes will be discussed in the section Cellular and Molecular Studies. 

Major depressive and bipolar disorders arise from the interactions between the susceptibility genes and environmental factors 888... 

In the field of molecular genetics, several susceptibility genes for breast cancer have been identified. The genes involved in the regulation of development... 

Miki, Y., et al., "A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1," Science, 266, 66-71 (1994). 

Study participation, treatment development based on, 8 Study populations, describing, 149 Subscriber agreements, 122 Succinylcholine, 60, 165, 168 Survey Questionnaire, General Population, 337-348 Susceptibility alleles, 52 Susceptibility genes, 44, 86 Susceptibility testing, 181, 306-307 Suter, Sonia, 17 Suxamethonium, 89, 139-140 Syphilis study, 68... 

Mapp, C. E. et al., Glutathione S-transferase GSTP1 is a susceptibility gene for occupational asthma induced by isocyanates, J. Allergy Clin. Immunol., 109, 867, 2002. 

Wanstrat, A. and Wakeland, E., The genetics of complex autoimmune diseases Non-MHC susceptibility genes, Nature Immunol., 2, 802, 2001. 

To identify environmental exposures which alter penetrance of cancer susceptibility genes and to quantify these gene-environment interactions. 

Shattuck-Eidens, D., et al., A collaborative survey of 80 mutations in the BRCAl breast and ovarian cancer susceptibility gene. Implications for presymptomatic testing and screening. Jama, 1995, 273(7), 535-41. 

Kinzler KW, Vogelstein B (1997) Cancer-susceptibility genes. Gatekeepers and caretakers. Nature... 

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