Surface modifiers additives

Cardiovascular-functional polymers cover almost all categories of synthetic polymers and large numbers of biopolymers. They are used to build the device bulk, act as surface-modifying additives [SMA], and also formulate tissue adhesives [11-17]. 

P.H. BUt, K.G. Battiston, K.A. Woodhouse, J.P. Santerre, Surface immobilization of elastin-like polypeptides using fluorinated surface modifying additives, J. Biomed. Mater. Res. 96 (2011) 648-662. 

There are numerous possibilities for the synthesis of polyurethanes, which provides a distinct advantage for tuning the polymer properties to specific applications. Table 4 overviews some possibilities. In addition, the use of surface-modifying additives (typically 1% or less by weight) in polyurethanes can enhance their biostability, or add other functionality to the polymers. ... 

Surface-modifying additives Biostability, blood compatibility... 

Gu, Y. J., Boonstra, P. W., Rijnsburger, A. A., Haan, J., and van Oeveren, W., Cardiopulmonary bypass circuit treated with surface-modifying additives Clinical evaluation of blood bicompalibility, Ann ThoraeSurg., 1998 65(5) 1342-1347. 

Figure 3.12 (a) OCP transients and (b) potentiodynamic polarization plots recorded at a scan rate of 5 mV/s using Ru and Cu disc samples in alkaline (pH = 10) test solutions containing different surface modifying additives. The line plots in (b) represent experimental data, and the symbols placed on these lines are used to label the different systems used. 

Tan J, Brash JL. Nonfouling biomaterials based on polyethylene oxide-containing amphiphilic triblock copolymers as surface modifying additives synthesis and characterization of copolymers and surface properties of copolymer-polyurethane blends. J Appl Polym Sci 2008 108 1617-28. 

Blit PH, Battiston KG, Woodhouse KA, Santerre JP. Surface immobilization of elastin-Uke polypeptides using fluorinated surface modifying additives. J Biomed Mater Res Part A March 15, 2011 96A(4) 648-62. 

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