Surface CD14 receptor

The differentiation effect of lycopene was associated with elevated expression of several differentiation-related proteins, such as cell surface antigen (CD14), oxygen burst oxidase and chemotactic peptide receptors (Amir et al., 1999). Recently, it has also been reported that lycopene was also able to stimulate the differentiation marker alkaline phosphatase activity in... 

Zasloff, M. Antimicrobial peptides of multicellular organisms. Nature 415 (2002) 389-395. Ziegler-Heitbrock, H.W., Ulevitch, R.J. CD14 cell surface receptor and differentiation marker. Immunol Today 14 (1993) 121-125. 

In patients with acute bacterial infections massive upregulation of activation-associated surface receptors was seen, including the high-affinity Fc receptor CD64 and the EPS receptor CD14, but in none of the patients was MHC class II found on PMN from the peripheral blood (fig. 2d). The patients... 

The initial events of the cellular response to LPS have now been characterised endotoxin responses are initiated by the binding of complexes of LPS and LPS-binding protein to CD14, which is a phos-phatidyhnositol-linked surface receptor present mainly in myelomonocytic cells (Schuman et al. 1990, Wright et al. 1990, Ziegler-Heitbrock et al. 1994). Subsequently, activation of these cells oc-... 

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