Sulph-10

M.p. B.p. Picrate M.p. Acetyl deiiv. M.p. Benzoyl deriv. H.p. Benzene sulph. Onyl deriv. M.p. Toluene p-sulph> onyl deny. M.p. Phenyl urea deriv, M.p. 

Numerous new salts and additive compounds of cinchona alkaloids, and especially of quinine, have been described, of which only a few can be mentioned as examples quinine additive compounds with sulph-anilamide, t quinine salts of (+) and (—)-pantothenic acid, °( > quinine sulphamate and disulphamate, °( organo-mercury compounds of quinine and cinchonine such as quinine-monomercuric chloride. Various salts and combinations of quinine have also been protected by patent, e.g., ascorbates and nicotinates. 

Amphetamines (speed sulph, sulphate, uppers, wake-ups, billy whizz, whizz, whites, base) are synthetic stimulants which as medicines have been formed into a variety of tablets. Their current medical use is very limited and in fact only dexamphetamine sulphate, Dexedrine, is now available for use solely in the treatment of narcolepsy. The only other amphetamine available for medical use is methylphenidate (Ritalin) for the treatment of attention deficit syndrome in children. As a street drug, amphetamine usually comes as a white, grey, yellowish or pinky powder. The purity rate of street powders is less than 10%, the rest being made up of milder stimulants such as caffeine, other drugs such as paracetamol or substances like glucose, dried baby milk, flour or talcum powder. 

Recently, N-aryl sulphimides were found to react with diphenyl cyclopropenone and its thione226 giving rise to imines 331 and 332. Apparently attack of the sulph-imide at cyclopropenone C3 gives rise to intermediacy of a ketene 330, which is consumed by an excess of the sulphimide (to give 331 after hydrolysis) or by its Somme-let-Hauser rearrangement (to give 332) ... 

Sulfex [Sulfide extraction] A process for removing heavy metals from waste streams by adding ferrous sulfide to precipitate them as their sulfides. Developed by the Permutit Company and now owned by U.S. Filter/Warrendale. Not to be confused with SULF-X or Sulph-X. 

SULF-X [Sulfur extraction] A regenerable flue-gas desulfurization process in which the sulfur dioxide is absorbed by aqueous sodium sulfide in a bed packed with pyrite. Ferrous sulfate is produced this is removed by centrifugation and calcined with coke and fresh pyrite. Sulfur vapor is evolved and condensed, and the residue is re-used in the scrubber. Piloted in the mid-1980s. Not to be confused with Sulfex or Sulph-X. 

Sulph-X A process for trapping sulfur in coal combustion. A proprietary mixture of inorganic salts, including sodium chloride, is mixed with the coal and combines with the sulfur dioxide so that it remains fixed in the ash instead of evolving with the combustion gases. Invented in China and developed in Australia in the 1990s by Coal Corporation Pty. Not to be confused with Sulfex or SULF-X. 

Toyo No. 50 Descending for 9 hrs 2% p-toluene sulph-onic acid in water saturated n-butanol 0.11- 0.20 0.23 )Separation )of neamine )from neo-)mycins B 204... 

Aspirin Salicylic Acid Dissolve 2.5 g in 25 ml alcohol (TS). To each of two matched cylinders add 48 ml of water and 1 ml of freshly prepared Ferric Ammonium Sulph. Reagent1. Into one cylinder pippete 1 ml of stand, salicylic acid soln. (0.01 % w/v in water) and into the other pipette 1 ml of TS. Mix the contents of the cylinder, after 30 secs, the colour of the second cylinder is not more intense than the first cylinder. NMT 0.1... 

I he first indication of a major structural change came wdien the positions of the mercury compounds attached to the two reactix e sulph-h3 dryl groups were determined. The two mercury atoms were found to be 37 A apart in reduced human haemoglobin coinjiared with a separation of 30 A for the same dcrix ative in horse oxyhaemoglobin (Table. 1). 

There is evidence that organotellurium compounds react with vicinal cysteine sulph-hydryl groups on squalene monooxygenase, plausibly because of the formation of unstable intermediates in which the tellurium atom is bonded to sulphhydryl groups in squalene... 

Many other non-peptide inhibitors of HIV protease (dihydropyrone, cyclic urea and sulphamide series of compounds) were obtained by modifications of random screening leads. Examples of these include a cyclic sulph-one derivative 147 and 148 (PNU-140690) that showed activity against a variety of HIV t)rpe 1... 

Solvent effects Different solvents have different effects on the nucleophilicity of a species. Solvents with acidic protons are called protic solvents, usually O—H or N—H groups. Polar protic solvents, e.g. dimethyl sulph-oxide (DMSO), dimethyl formamide (DMF), acetonitrile (CH3CN) and acetone (CH3COCH3) are often used in 8 2 reactions, since the polar reactants (nucleophile and alkyl halide) generally dissolve well in them. 

Table 6. Electrical Conductivity cf the S5rsfcem Nitrobertaene-Sulph me Acid ...

Treatment Carbo veg 200, Sulphur 30, 200, Carbo veg 500, Natrum sulph 1000, Acid Nitric 1000. Treatment continued for 7 months and the patient was... 

Sulph(on)ation processes. Since many of the anionic surfactants to be discussed are made by the addition of S03 to an organic substrate, it is appropriate to consider, in overview, the main processes used and the contribution of the sulphonation process to the quality and performance of the surfactant. (The term sulphonation is used here generically to describe reaction of an organic with SO3, regardless of the nature of the substrate.)... 

Nitration of phenol. The process is effected in two stages. The first is the sulph-onation of the phenol, followed by acting with nitric acid on a solution of phenolsul-phonic acid in sulphuric acid. In the latter process the sulpho groups are replaced by nitro groups (p. 501). This indirect procedure has to be adopted because the direct action of nitric acid on phenol yields undesirable by-products, sometimes brightly coloured, which contaminate the principal product. 

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