Sulfated galactans isolation

Farias, W. R., Valente, A. P., Pereira, M. S., and Mourao, P. A. (2000). Structure and anticoagulant activity of sulfated galactans. Isolation of a unique sulfated galactan from the red algae Botryocladia occidentalis and comparison of its anticoagulant action with that of sulfated galactans from invertebrates.. Biol. Chem. 275, 29299-29307. 

Farias, W.R.L. et al. (2000) Structure and anticoagulant activity of sulfated galactans - isolation of a unique sulfated galactan from the... 

Marine sulfated polysaccharides (MSPs), such as sulfated fucans (SFs), sulfated galactans (SGs), and glycosaminoglycans (GAGs) isolated from invertebrate animals, are highly anionic polysaccharides capable of interacting with certain cationic proteins, such as... 

In addition to valuable physicochemical properties, sulfated polysaccharides of the red algae are promising biologically active polymers, and many structural works already cited aimed at isolation and characterization of new compounds having potential medical application. The most important types of biological activity of sulfated galactans are listed briefly in this section. 

A highly ramified pyruvylated sulfated galactan was isolated from a Japanese Codium fragile. This sulfated polysaccharide is active against herpes simplex type II and stimulates macrophage (Lee et al, 2010). 

K. Chattopadhyay, C. G. Mateu, P. Mandal, C. A. Pujol, E. B. Damonte, and B. Ray, Galactan sulfate of Grateloupia indica Isolation, structural features and antiviral activity, Phytochemistry, 68 (2007) 1428-1435. 

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