Sucrose octaacetate

Bachmanov, A. A. et al. High-resolution genetic mapping of the sucrose octaacetate taste aversion (Soa) locus on mouse Chromosome 6. Mamm. Genome. 12 695-699, 2001. 

Although the above condensations definitely failed to yield sucrose octaacetate, Irvine and his collaborators showed that they did produce, in addition to uncrystallized products, some D-glucose pentaacetate, some... 

The most important of the acyl derivatives of sucrose is doubtless sucrose octaacetate. This is represented by formula LXIV, the consti-... 

Fig. 4. (a) Conventional 500 MHz HMBC spectrum of sucrose octaacetate in deuteriochlo-roform, and (b) HMBC spectrum with ti-noise corrected by reference deconvolution. (Reproduced, with permission, from Signal Treatment and Signal Analysis in NMR, ed. D.N. Rutledge, Elsevier, Amsterdam, 1996)... 

Recently, studies were reported measuring the kinetics of stimulation of both cAMP and 3 using a mixing device and rapid quenching, in the millisecond range, in rat olfactory cilia (67). The response to a mixture of < orants peaks within 25 to 50 milliseconds, the time frame expected for receptors, with both cAMP and IP3. Similar measurements of the change in concentration of cAMP or IP3 were also done in the taste cell. Here mice, which were bred as bitter tasters and nontasters , were used as subjects. The bitter stimuli, sucrose octaacetate, strychnine and denatonium benzoate, were shown to increase IP3 levels in a membrane preparation from "taster" mice in the presence of GTP-protein and Ca but not in membranes from "nontaster" mice (68). 

Figu re 6.7 Regioselective deacylation of sucrose octaacetate (27) catalyzed by different hydrolases. 

Attempts have been made to solve the problem of selective substitution in sucrose octaacetate. Adsorption of the latter onto alumina for 46 hours gave a complex mixture from which, after extensive chromatography, were isolated the 2,3,4,6,l, 3, 4 -heptaacetate in 9% yield,11 the 2,3,6,l, 3, 4, 6 -heptaacetate in 2.7% yield,117 and the 2,3,4,6,1, 3, 6 -heptaacetate in 6% yield.117 Although selective deacylation of the octaacetate apparently occurs at secondary positions, as well as at 0-6, it is likely that heptaacetates containing 4- and 4 -OH groups... 

D. Zinc Reduction-Volumetric Procedure (Ref 3, Method 203-5). It is used for detg DEtPh. or DBuPh content of proplnts that do not contain interfering esters such as other phthalates, dimethyl sebacate, tri-acetin, or sucrose octaacetate... 

Electron tunneling from the first singlet excited state of pentacene to duroquinone in sucrose octaacetate glass was discovered [80] by observing the time dependence of fluorescence emission. The tunneling distance,... 

As mentioned in Section 8.3.2, the instrument must be calibrated with a substance of known molecular weight. The experimental conditions, i.e., solvent and temperature, must be strictly identical with those used for lignin samples. The calibrating substances usually employed are benzil (M = 210.2 g mol ) and sucrose octaacetate (M = 678.6 gmol ) with concentrations, m, in the range between 10 2 and 10 molkg-1. 

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