Studies Polymer Additives in Pharmaceutical Packaging

CASE STUDIES POLYMER ADDITIVES IN PHARMACEUTICAL PACKAGING [Pg.315]

Additionally, subsequent analysis of the materials for compliance to various regulations is based on solvent extraction protocols followed by GC/FID (flame ionization detector) analysis. These protocols are generally based on specific target compounds that are regulated rather than analysis for all compounds present. From our experience we have documented many problems related to such an approach. The following case studies emphasize the need for thoroughly analyzing materials for suitability early on in the developmental process. [Pg.315]

Injectable pharmaceutical compounds are often pre-packaged into vials that are inserted into syringe barrels for patient delivery. In some cases, the vials contain contaminants. In the present example, the active compound inside this vial was sampled and found to contain acetophenone, dibutyl phthalate, stearic acid, and myristic acid, none of which are components of the drug [Pg.405]

Handbook for the Chemical Analysis of Plastic and Polymer Additives [Pg.406]

Big Chemical Encyclopedia