Strongyloides ratti

Viney, M. (1994) A genetic analysis of reproduction in Strongyloides ratti. Parasitology 109,511-515. 

Viney, M.E. (1996) Developmental switching in the parasitic nematode Strongyloides ratti. Proceedings of the Royal Society of London, Series B 263, 201-208. 

Viney, M.E. (1999) Exploiting the life cycle of Strongyloides ratti. Parasitology Today 15,... 

Strongyloides ratti has two developmental routes in its life cycle (Fig. 5.1) and this developmental choice shows phenotypic diversity. The parasitic phase of S. ratti is a parthenogenetic female (Viney, 1994). Eggs that pass out of a host can complete the free-living phase of the life cycle by two alternative developmental routes, termed heterogonic and homogonic. In homogonic... 

Fig. 5.1. The life cycle of Strongyloides ratti. The progeny of the parasitic female can develop by two different routes, termed heterogonic and homogonic. L, larval stage.

Gemmil, AW., Viney, M.E. and Read, A.F. (2000) The evolutionary ecology of host-specificity experimental studies with Strongyloides ratti. Parasitology 120, 429-437. 

Viney, M.E., Matthews, B.E. and Walliker, D. (1992) On the biological and biochemical nature of cloned populations of Strongyloides ratti. Journal of Helminthology 66, 45-52. 

Abe, T. and Nawa, Y. (1988) Worm expulsion and mucosal mast cell response induced by repetitive IL-3 administration in Strongyloides ratti-infected nude mice. Immunology 63, 181-185. 

Watanabe K, Noda K, Hamano S, Koga M, Kishihara K, Nomoto K, Tada I The crucial role of granulocytes in the early host defense against Strongyloides ratti infection in mice. Parasitol Res 2000 86 188-193. 

The impact of anti-IgE antibodies on parasite burdens has been examined in animal models of infections with 5. mansoni, the lung fluke Paragonimus wetermani, and Strongyloides ratti. Despite undetectable levels of IgE posttreatment, treatment with anti-IgE resulted in reduced parasite burdens in mice infected with P. westermani (95) and decreased worm burden and a decrease in the number of eggs produced per worm in mice infected with S. mansoni (96). Experimental infections with S. ratti were not affected by anti-IgE treatment (97). Potential... 

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