Stress response proteins

C. M. Payne, C. Crowley, D. Washo-Stultz, M. Briehl, H. Bernstein, C. Bernstein, S. Beard, Ft. Holubec and J. Warneke, The stress-response proteins poly(ADP-ribose) polymerase and NF-kappaB protect against bile salt-induced apoptosis, Cell Death Dijfer., 1998, 5(7), 623. 

Another type of stress response protein is related to glutathione S-transferase 462 Cells of E. coli also accumulate a 15.8-kDa universal stress protein in... 

The mechanistic basis of the neuroprotective activity of FAEE appears to rely not only on its general free-radical trapping or antioxidant activity per se, but also on its activity in mediating the induction of stress response proteins (HO-1 and F1SP72), cytoprotective (phase 2) proteins, and the parallel suppression of genes induced by pro-inflammatory cytokines, such as nitric oxide synthase (iNOS). 

FAEE is also neuroprotective by leading to elevated levels of stress response proteins, such as HO-1 and HSP72. 

Stress Response Proteins and Other Marker Proteins.195... 

When organisms are confronted with sudden changes such as exposure to potentially toxic substances (heavy metal ions) or the onset of starvation, these stimulations induce the production of the so-called stress responsive proteins. The most thoroughly studied stress proteins include the heat-shock proteins (HSP), the induction of which is a highly conserved response across genera. 

Faria D, Lentze N, Almafa J et al (2012) Regulation of ENaC biogenesis by the stress response protein SERP1. Pflugers Arch 463(6) 819-827... 

Heat shock proteins (Hsp), stress-response proteins, a group of highly conserved proteins in both prokaryotes and eukaryotes, formed in response to hyperthermia or other noxious conditions. Almost all Hsp function as molecular chaperones. According to their molecular weight (in kDa), the Hsp are divided into six main families. (1) HsplOO belongs to the AAA + protein super family (adenosine triphosphatases with diverse activities) sharing a common... 

Consequentially to the marine environment due to an enigmatic transition from terrestrial to full aquatic habitat, the entire set of stress response proteins had to change and adapt. The innate TLR4 poised at the interface between host and an entirely new microbial environment has undergone a profound adaptive evolution ... 

Post translation unfolded protein, are bound by heat shock proteins (HSPs), such as HSP70 and HSP90 binds which facilitate their proper folding in cytoplasm (Pratt and Morishima 2010). However, not all proteins are folded properly, and high acciunulations of unfolded or mis-folded are reported to cause intracellular toxicity and to contribute to cell death (iageretal. 2012 Loewen and Feany 2010). These misfolded or unfolded proteins are trapped in cytoplasm or the ER and induce the expression of stress response proteins, such as HSPs, IRE, PERK, and ATF-6 (Badiola et a/. 2011 Gorman eto/. 2012). 

Bae, H., Herman, E., and Sicher, R. (2005). Endogenous trehalose promotes non-structural carbohydrate accumulation and induces chemical detoxification and stress response proteins in Arabidopsis thaliana grown in liquid culture. Plant Sci. 168, 1293-1301. 

Khedr AA, Abbas MA, Abdel Wahid AA, Quick WP, Abogadallah GM (2003) Prohne induces the expression of salt-stress-responsive proteins and may improve the adaptation of Pancratium maritimum L. to salt-stress. J Exp Bot 54 2553-2562 Laszlo R, Csaba H (2004) Iodine and selenium intake from soil to cultivated mushrooms, 2nd international symposium - trace elements in food, Brussels, Belgium, 7-8 October, Abstracts, European Commission Joint Research Centre, Brussels, Belgium, p 21 Lemly AD (1993) Guidelines for evaluating selenium data from aquatic monitoring and assessment studies. Environ Monit Assess 28 83-100... 

The multitude of cellular signaling pathways involved in stress responses is entangled with other signaling pathways, such as those in cell death and ceU survival, and cannot be separated in their entirety. The stress response protein, metaUothionein, which is integral in Cd " detoxification has been covered in Sections 2-4 and 6 as well as in Chapters 1 and 11 of this book. 

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