Strategies for Pulmonary Delivery

A nanoparticle is a microscopic particle with a diameter less than 100 nm. Nanoparticles were first developed around 1970, and initially they were devised as carriers for vaccines and anticancer drugs. Nanoparticle research is currently an area of intense scientific research because of a wide variety of potential applications in biomedical, optical, and electronic fields. To enhance tumor uptake, the strategy of drug targeting was employed, and as a first important step, research focused on the development of methods to reduce the uptake of the nanoparticles by the RES cells. Simultaneously, the use of nanoparticles for ophthalmic and oral delivery was investigated (17, 18). Recent advancement of nanoparticles and nanosuspensions was caused by their application for pulmonary drug delivery (19, 20). 

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