Strasbourg Structural chemistry

The Nobel Prize for Chemistry in 1987 was awarded to Charles J. Pedersen (retired from DuPont company), Donald J. Cram (retired from the University of California, Los Angeles), and Jean-Marie Lehn (Louis Pasteur University, Strasbourg, France) for their development of crown ethers and other molecules with structure specific interactions of high selectivity . 

Jean-Marie Lehn has a joint appointment as Professor at the Institut Le Bel, Universite Louis Pasteur in Strasbourg and at the College de France in Paris. Donald J. Cram (1919-2001), Jean-Marie Lehn (b. 1939), and Charles J. Pedersen (1904-1989) received the Chemistry Nobel Prize in 1987 for their development and use of molecules with structure-specific interactions with high selectivity. The conversation with Professor Lehn took place during a brief Budapest visit of his on May 8, 1995. The interview was squeezed in between a press conference and a lecture, and the schedule was running late. ... 

The foundation for HTRF lies in the Nobel prize chemistry of Professor Jean Marie Lehn (Strasbourg University) [1]. This chemistry was further developed by Professor Lehn and Dr. Gerard Mathis (CIS bio international) into a europium cryptate (EuK) based assay technology (Figure 1). This innovative structure has five distinct and critically important functions ... 

This stabilization was carried to extremes in work that ultimately led to the 1987 Nobel Prize in Chemistry for Charles J. Pedersen (1904—1989) of du Pont, Donald J. Cram (1919-2001) of UCLA, and Jean-Marie Lehn (b. 1939) of Universite Louis Pasteur in Strasbourg for opening the field of host-guest chemistry. Pedersen discovered that certain cyclic polyethers (the hosts) had a remarkable affinity for metal cations (the guests). Molecules were constructed whose molecular shapes created different-sized cavities into which different metal ions fit well. Because of their vaguely crown-shaped structures, these molecules came to be called crown ethers. Rgure 6.60 shows two of them. 

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