Stoichiometric saturation, definition

These activities can be verified if It can he shown that the solubility data of (8) are at stoichiometric saturation, but as mentioned above, this requires independent thermodynamic definition of K(x). 

According to Thorstenson and Plummer s (1) definition of stoichiometric saturation, an aqueous-solution at thermodynamic equilibrium with respect to a solid Bi.xCxA will always be at stoichiometric saturation with respect to that same solid. The converse statement, however, is not necessarily true stoichiometric saturation does not necessarily imply thermodynamic equilibrium. 

The definition of the saturation ratio originates from the description of the driving force for precipitation from stoichiometric solutions in which S = ajaK. cjcv where a and c,. are the mean ion activities in a supersaturated and equilibrium solution, respectively, and c and ct are the corresponding concentrations, e.g. the saturation ratio of a silver chloride solution is... 

Have all the proteins required for initiation now been identified There is no doubt that the seven factors are sufficient to promote initiation, but in comparison with the crude reticulocyte lysate these systems that use purified components function at a very slow rate - of the order of 0 (II). Moreover, the amounts of initiation factors required to obtain maximal rates in the fractionated system seem very hi. Although there are no firm estimates of the concentrations of initiation factors in crude lysates, few would dispute that they are probably lower than the levels used in fractionated systems, where, with one exception, the relationship between the quantities of factors added and the number of initiation events is such that each molecule of factor might function only once in a stoichiometric manner. The exception is eIF-5 which saturates at low levels and definitely acts catalytically. For the other factors, the explanation may be that there is a large fraction of denatured factor which is defective in catalysing the correct overall reaction, but can interfere with the action of the fully active factor, and thereby cause a low rate of... 

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